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OncoImmunology

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Oncoimmunology publishes international translational and clinical research into tumor immunology including anticancer therapies and immunotherapies.
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OncoImmunology, Volume 9, Issue 1 (2020)

Issue In Progress

Original Research

旺财体育
Baseline plasma levels of soluble PD-1, PD-L1, and BTN3A1 predict response to nivolumab treatment in patients with metastatic renal cell carcinoma: a step toward a biomarker for therapeutic decisions
Lorena Incorvaia , Daniele Fanale , Giuseppe Badalamenti , Camillo Porta , Daniel Olive , Ida De Luca , Chiara Brando , Mimma Rizzo , Carlo Messina , Mattia Rediti , Antonio Russo , Viviana Bazan & Juan Lucio Iovanna
旺财体育: 1832348
Published online: 27 Oct 2020
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  • 19Views
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旺财体育
Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers
Soleine Medjebar , Caroline Truntzer , Ana茂s Perrichet , Emeric Limagne , Jean-David Fumet , Corentin Richard , Arielle Elkrief , Bertrand Routy , C茅dric R茅b茅 & Fran莽ois Ghiringhelli
旺财体育: 1836766
Published online: 27 Oct 2020
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  • 5Views
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旺财体育
Tumor-infiltrating TNFRSF9+ CD8+ T cells define different subsets of clear cell renal cell carcinoma with prognosis and immunotherapeutic response
Yaohui Li , Zewei Wang , Wenbin Jiang , Han Zeng , Zhaopei Liu , Zhiyuan Lin , Yang Qu , Ying Xiong , Jiajun Wang , Yuan Chang , Qi Bai , Yiwei Wang , Li Liu , Yu Zhu , Le Xu , Yu Xia , Jianming Guo & Jiejie Xu
旺财体育: 1838141
Published online: 27 Oct 2020
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  • 6Views
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旺财体育
IAP inhibitor, Embelin increases VCAM-1 levels on the endothelium, producing lymphocytic infiltration and antitumor immunity
Kosei Nakajima , Yoshinori Ino , Rie Yamazaki-Itoh , Chie Naito , Mari Shimasaki , Mami Takahashi , Minoru Esaki , Satoshi Nara , Yoji Kishi , Kazuaki Shimada & Nobuyoshi Hiraoka
旺财体育: 1838812
Published online: 27 Oct 2020
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  • 9Views
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旺财体育
Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death
L铆gia C. Gomes-da-Silva , Oliver Kepp & Guido Kroemer
旺财体育: 1841393
Published online: 27 Oct 2020
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旺财体育
Resveratrol exerts antitumor effects by downregulating CD8+CD122+ Tregs in murine hepatocellular carcinoma
Qunfang Zhang , Haiding Huang , Fang Zheng , Huazhen Liu , Feifei Qiu , Yuchao Chen , Chun-Ling Liang & Zhenhua Dai
旺财体育: 1829346
Published online: 24 Oct 2020
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  • 60Views
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旺财体育
Reduction of CD11b+ myeloid suppressive cells augments anti-neuroblastoma immune response induced by the anti-GD2 antibody ch14.18/CHO
Nikolai Siebert , Maxi Zumpe , Leon von Lojewski , Sascha Troschke-Meurer , Madlen Marx & Holger N. Lode
旺财体育: 1836768
Published online: 24 Oct 2020
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  • 87Views
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旺财体育
Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade
Karsten A. Pilones , Michal Hensler , Camille Daviaud , Jeffrey Kraynak , Jitka Fucikova , Lorenzo Galluzzi , Sandra Demaria & Silvia C. Formenti
旺财体育: 1830524
Published online: 20 Oct 2020
Abstract | Full Text | References | PDF (2085 KB) | Supplemental | Permissions聽

  • 166Views
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旺财体育
Single-cell analysis reveals immune modulation and metabolic switch in tumor-draining lymph nodes
Yen-Liang Li , Chung-Hsing Chen , Jing-Yi Chen , You-Syuan Lai , Shao-Chun Wang , Shih-Sheng Jiang & Wen-Chun Hung
旺财体育: 1830513
Published online: 19 Oct 2020
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  • 185Views
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旺财体育
Immune infiltration and immune gene signature predict the response to fluoropyrimidine-based chemotherapy in colorectal cancer patients
Xianwei Mo , Xiaoliang Huang , Yan Feng , Chunyin Wei , Haizhou Liu , Haiming Ru , Haiquan Qin , Hao Lai , Guo Wu , Weishun Xie , Franco Jeen , Yuan Lin , Jungang Liu & Weizhong Tang
旺财体育: 1832347
Published online: 19 Oct 2020
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  • 105Views
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旺财体育
Small-molecule PD-L1 inhibitor BMS1166 abrogates the function of PD-L1 by blocking its ER export
Fang-Fang Chen , Zheng Li , Dawei Ma & Qiang Yu
旺财体育: 1831153
Published online: 14 Oct 2020
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  • 167Views
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Author鈥檚 View

No time to die: the consensus immunoscore for predicting survival and response to chemotherapy of locally advanced colon cancer patients in a multicenter international study
Paolo A. Ascierto , Francesco M. Marincola , Bernard A. Fox & J茅r么me Galon
旺财体育: 1826132
Published online: 13 Oct 2020
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  • 307Views
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Immunity to live: an immunopathoscore using the consensus Immunoscore to best define the risk of recurrence and death in stage IV metastatic patients
Pamela Baldin , Marc Van den Eynde , Bernhard Mlecnik & J茅r么me Galon
旺财体育: 1826133
Published online: 13 Oct 2020
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  • 102Views
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Usefulness and robustness of Immunoscore for personalized management of cancer patients
Florence Marliot , Franck Pag猫s & J茅r么me Galon
旺财体育: 1832324
Published online: 13 Oct 2020
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  • 108Views
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Original Research

旺财体育
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis
Sandrine Nugteren , Jeroen A.C.M. Goos , Pien M. Delis-van Diemen , Ytje Simons-Oosterhuis , Dicky J. Lindenbergh-Kortleve , Dani毛lle H. van Haaften , Joyce Sanders , Gerrit A. Meijer , Remond J.A. Fijneman & Janneke N. Samsom
旺财体育: 1832761
Published online: 13 Oct 2020
Abstract | Full Text | References | PDF (8281 KB) | Supplemental | Permissions聽

  • 171Views
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Review

RNA-electroporated T cells for cancer immunotherapy
Fernanda Pohl-Guimar茫es , Lan B. Hoang-Minh & Duane A. Mitchell
旺财体育: 1792625
Published online: 07 Oct 2020
Abstract | Full Text | References | PDF (3463 KB) | Permissions聽

  • 191Views
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Original Research

旺财体育
Significantly different immunoscores in lung adenocarcinoma and squamous cell carcinoma and a proposal for a new immune staging system
Ziqing Zeng , Fan Yang , Yunliang Wang , Hua Zhao , Feng Wei , Peng Zhang , Xiying Zhang & Xiubao Ren
旺财体育: 1828538
Published online: 07 Oct 2020
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  • 121Views
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旺财体育
Association of baseline systemic corticosteroid use with overall survival and time to next treatment in patients receiving immune checkpoint inhibitor therapy in real-world US oncology practice for advanced non-small cell lung cancer, melanoma, or urothelial carcinoma
Alexandra Drakaki , Preet K Dhillon , Heather Wakelee , Stephen Y Chui , Jinjoo Shim , Matthew Kent , Viraj Degaonkar , Tien Hoang , Virginia McNally , Patricia Luhn & Ralf Gutzmer
旺财体育: 1824645
Published online: 05 Oct 2020
Abstract | Full Text | References | PDF (987 KB) | Supplemental | Permissions聽

  • 281Views
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旺财体育
Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model
Pravin T. P. Kaumaya , Linlin Guo , Jay Overholser , Manuel L. Penichet & Tanios Bekaii-Saab
旺财体育: 1818437
Published online: 01 Oct 2020
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  • 557Views
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旺财体育
Cancer testis antigens in myelodysplastic syndromes revisited: a targeted RNA-seq approach
Ana Mar铆a Hurtado L贸pez , Tzu Hua Chen-Liang , Mar铆a Zurdo , Salvador Carrillo-Tornel , Joaqu铆n Panadero , Eduardo Jos茅 Salido , Victor Beltr谩n , Bego帽a Mui帽a , MariLuz Amigo , Noelia Navarro-Villamor , Rosa Cifuentes , In茅s Calabria , Ana Isabel Ant贸n , Ra煤l Teruel , Manuel Muro , Vicente Vicente & Andr茅s Jerez
旺财体育: 1824642
Published online: 01 Oct 2020
Abstract | Full Text | References | PDF (2494 KB) | Supplemental | Permissions聽

  • 170Views
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旺财体育
Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression
M. P枚tzsch , E. Berg , M. Hummel , U. Stein , M. von Winterfeld , K. J枚hrens , B. Rau , S. Daum & C. Treese
旺财体育: 1824632
Published online: 30 Sep 2020
Abstract | Full Text | References | PDF (9477 KB) | Supplemental | Permissions聽

  • 174Views
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旺财体育
Tivozanib mediated inhibition of c-Kit/SCF signaling on Tregs and MDSCs and reversal of tumor induced immune suppression correlates with survival of HCC patients
Suresh Gopi Kalathil , Katy Wang , Alan Hutson , Renuka Iyer & Yasmin Thanavala
旺财体育: 1824863
Published online: 30 Sep 2020
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  • 218Views
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旺财体育
Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis
Varun Sasidharan Nair , Reem Saleh , Rowaida Z Taha , Salman M Toor , Khaled Murshed , Ayman A Ahmed , Mohamed A Kurer , Mohamed Abu Nada , Fares Al Ejeh & Eyad Elkord
旺财体育: 1825178
Published online: 30 Sep 2020
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  • 209Views
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Author鈥檚 View

旺财体育
Multiverse of immune microenvironment in metastatic colorectal cancer
Marc Van den Eynde , Bernhard Mlecnik , Gabriela Bindea & J茅r么me Galon
旺财体育: 1824316
Published online: 29 Sep 2020
Abstract | Full Text | References | PDF (964 KB) | Permissions聽

  • 115Views
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Original Research

旺财体育
Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRP伪 鈥渄on鈥檛 eat me鈥� immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-presentation
Mark A. J. M. Hendriks , Emily M. Ploeg , Iris Koopmans , Isabel Britsch , Xiurong Ke , Douwe F. Samplonius & Wijnand Helfrich
旺财体育: 1824323
Published online: 29 Sep 2020
Abstract | Full Text | References | PDF (4165 KB) | Supplemental | Permissions聽

  • 279Views
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旺财体育
Identification of a costimulatory molecule-based signature for predicting prognosis risk and immunotherapy response in patients with lung adenocarcinoma
Chaoqi Zhang , Zhihui Zhang , Nan Sun , Zhen Zhang , Guochao Zhang , Feng Wang , Yuejun Luo , Yun Che & Jie He
旺财体育: 1824641
Published online: 29 Sep 2020
Abstract | Full Text | References | PDF (5943 KB) | Supplemental | Permissions聽

  • 134Views
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旺财体育
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Mari Tinholt , Benedicte Stavik , Xavier Tekpli , 脴ystein Garred , Elin Borgen , Vessela Kristensen , Kristine Kleivi Sahlberg , Per Morten Sandset & Nina Iversen
旺财体育: 1824644
Published online: 29 Sep 2020
Abstract | Full Text | References | PDF (7608 KB) | Supplemental | Permissions聽

  • 176Views
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Brief Report

brief report
Adapter chimeric antigen receptor (AdCAR)-engineered NK-92 cells: an off-the-shelf cellular therapeutic for universal tumor targeting
Stefan Grote , Joerg Mittelstaet , Caroline Baden , Kenneth Chun-Ho Chan , Christian Seitz , Patrick Schlegel , Andrew Kaiser , Rupert Handgretinger & Sabine Schleicher
旺财体育: 1825177
Published online: 29 Sep 2020
Abstract | Full Text | References | PDF (2666 KB) | Permissions聽

  • 269Views
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Original Research

旺财体育
Improving the anti-solid tumor efficacy of CAR-T cells by inhibiting adenosine signaling pathway
Na Li , Na Tang , Chen Cheng , Tao Hu , Xiaofei Wei , Weidong Han & Haoyi Wang
旺财体育: 1824643
Published online: 24 Sep 2020
Abstract | Full Text | References | PDF (4088 KB) | Supplemental | Permissions聽

  • 319Views
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旺财体育
Pirfenidone facilitates immune infiltration and enhances the antitumor efficacy of PD-L1 blockade in mice
Wan Qin , Jun Zou , Yongbiao Huang , Chaofan Liu , Yalin Kang , Hu Han , Yang Tang , Long Li , Bo Liu , Weiheng Zhao & Xianglin Yuan
旺财体育: 1824631
Published online: 22 Sep 2020
Abstract | Full Text | References | PDF (8789 KB) | Supplemental | Permissions聽

  • 240Views
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旺财体育
Immunotherapy or other anti-cancer treatments and risk of exacerbation and mortality in cancer patients with COVID-19: a systematic review and meta-analysis
Bolin Wang & Yan Huang
旺财体育: 1824646
Published online: 22 Sep 2020
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  • 214Views
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Brief Report

brief report
Anti-GD2 antibody and Vorinostat immunocombination therapy is highly effective in an aggressive orthotopic neuroblastoma model
Renske J. E. van den Bijgaart , Michiel Kroesen , Ingrid C. Brok , Daphne Reijnen , Melissa Wassink , Louis Boon , Peter M. Hoogerbrugge & Gosse J Adema
旺财体育: 1817653
Published online: 20 Sep 2020
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  • 225Views
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Original Research

旺财体育
Live-attenuated lymphocytic choriomeningitis virus-based vaccines for active immunotherapy of HPV16-positive cancer
Sarah Schmidt , Weldy V. Bonilla , Andrea Reiter , Felix Stemeseder , Theresa Kleissner , Daniel Oeler , Ursula Berka , Ahmed El-Gazzar , Bettina Kiefmann , Sophie C. Schulha , Josipa Raguz , Mohamed Habbeddine , Marilies Scheinost , Xiaoping Qing , Henning Lauterbach , Igor Matushansky , Daniel D. Pinschewer & Klaus K. Orlinger
旺财体育: 1809960
Published online: 15 Sep 2020
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  • 779Views
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Research 旺财体育

旺财体育
Pan-TGF尾 inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade
Rita Greco , Hongjing Qu , Hui Qu , Joachim Theilhaber , Gary Shapiro , Richard Gregory , Christopher Winter , Natalia Malkova , Frank Sun , Julie Jaworski , Annie Best , Lily Pao , Andrew Hebert , Mikhail Levit , Alexei Protopopov , Jack Pollard , Keith Bahjat , Dmitri Wiederschain & Sharad Sharma
旺财体育: 1811605
Published online: 13 Sep 2020
Abstract | Full Text | References | PDF (9780 KB) | Supplemental | Permissions聽

  • 1129Views
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Author鈥檚 View

Reviving the role of MET in liver cancer therapy and vaccination: an autophagic perspective
Xing Huang , Gang Zhang , Xueli Bai & Tingbo Liang
旺财体育: 1818438
Published online: 13 Sep 2020
Abstract | Full Text | References | PDF (612 KB) | Permissions聽

  • 152Views
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Original Research

旺财体育
Identification of novel autoantibodies based on the protein chip encoded by cancer-driving genes in detection of esophageal squamous cell carcinoma
Guiying Sun , Hua Ye , Xiao Wang , Lin Cheng , Pengfei Ren , Jianxiang Shi , Liping Dai , Peng Wang & Jianying Zhang
旺财体育: 1814515
Published online: 09 Sep 2020
Abstract | Full Text | References | PDF (1613 KB) | Supplemental | Permissions聽

  • 160Views
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Brief report

brief report
Robust antigen-specific CD8 T cell tolerance to a model prostate cancer neoantigen
Zoila A. Lopez-Bujanda , Matthew G. Chaimowitz , Todd D. Armstrong , Jeremy B. Foote , Leisha A. Emens & Charles G. Drake
旺财体育: 1809926
Published online: 06 Sep 2020
Abstract | Full Text | References | PDF (4024 KB) | Supplemental | Permissions聽

  • 349Views
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Research 旺财体育

旺财体育
Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response
Hiroaki Mashima , Rong Zhang , Tsuyoshi Kobayashi , Yuichiro Hagiya , Hirotake Tsukamoto , Tianyi Liu , Tatsuaki Iwama , Masateru Yamamoto , Chiahsuan Lin , Ryusuke Nakatsuka , Yuta Mishima , Noriko Watanabe , Takashi Yamada , Satoru Senju , Shin Kaneko , Alimjan Idiris , Tetsuya Nakatsura , Hideki Ohdan & Yasushi Uemura
旺财体育: 1814620
Published online: 06 Sep 2020
Abstract | Full Text | References | PDF (14028 KB) | Supplemental | Permissions聽

  • 616Views
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Review

Immunotherapy with NK cells: recent developments in gene modification open up new avenues
Lisa Marie Reindl , Nawid Albinger , Tobias Bexte , Stephan M眉ller , Jessica Hartmann & Evelyn Ullrich
旺财体育: 1777651
Published online: 02 Sep 2020
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  • 480Views
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Author鈥檚 view

Firing up the cold tumors by targeting Vps34
Bassam Janji , Meriem Hasmim , Santiago Parpal , Guy Berchem & Muhammad Zaeem Noman
旺财体育: 1809936
Published online: 31 Aug 2020
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  • 671Views
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Brief Report

brief report
尾-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer
Caihong Wang , Jingjing Yan , Pan Yin , Liming Gui , Lu Ji , Bin Ma & Wei-Qiang Gao
旺财体育: 1809947
Published online: 31 Aug 2020
Abstract | Full Text | References | PDF (2379 KB) | Supplemental | Permissions聽

  • 474Views
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Original research

旺财体育
An integrated classifier improves prognostic accuracy in non-metastatic gastric cancer
Xiaofang Xing , Shuqin Jia , Yuxin Leng , Qian Wang , Zhongwu Li , Bin Dong , Ting Guo , Xiaojing Cheng , Hong Du , Ying Hu , Qin Feng , Shenyi Lian , Fengming Luan , Xiaoxiao Ma , Zhe Li , Ming Ni , Ziyu Li & Jiafu Ji
旺财体育: 1792038
Published online: 30 Aug 2020
Abstract | Full Text | References | PDF (6045 KB) | Supplemental | Permissions聽

  • 327Views
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Brief report

brief report
Primary and metastatic breast tumors cross-talk to influence immunotherapy responses
Amanda J Oliver , Simon P Keam , Bianca von Scheidt , Damien J Zanker , Aaron J Harrison , Daniela GM Tantalo , Phillip K Darcy , Michael H Kershaw & Clare Y Slaney
旺财体育: 1802979
Published online: 30 Aug 2020
Abstract | Full Text | References | PDF (4590 KB) | Supplemental | Permissions聽

  • 295Views
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Original research

旺财体育
Human innate immune cell crosstalk induces melanoma cell senescence
Felix Funck , Jens Pahl , Lenka Kyjacova , Lukas Freund , Stephanie Oehrl , Galina Gr盲be , Silvia Pezer , Jessica C. Hassel , Jonathan Sleeman , Adelheid Cerwenka & Knut Sch盲kel
旺财体育: 1808424
Published online: 30 Aug 2020
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  • 272Views
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旺财体育
PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates
Yago Pico de Coa帽a , Maria Wolodarski , Irene van der Haar 脌vila , Takahiro Nakajima , Stamatina Rentouli , Andreas Lundqvist , Giuseppe Masucci , Johan Hansson & Rolf Kiessling
旺财体育: 1786888
Published online: 28 Aug 2020
Abstract | Full Text | References | PDF (1756 KB) | Supplemental | Permissions聽

  • 723Views
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Original Research

旺财体育
Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis
Baihui Li , Bailu Zhang , Xuezhou Wang , Ziqing Zeng , Ziqi Huang , Lin Zhang , Feng Wei , Xiubao Ren & Lili Yang
旺财体育: 1807291
Published online: 28 Aug 2020
Abstract | Full Text | References | PDF (5428 KB) | Supplemental | Permissions聽

  • 871Views
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Original research

旺财体育
Identification and validation of an excellent prognosis subtype of muscle-invasive bladder cancer patients with intratumoral CXCR5+ CD8+ T cell abundance
Qiuren Huang , Quan Zhou , Hongyu Zhang , Zhaopei Liu , Han Zeng , Yifan Chen , Yang Qu , Ying Xiong , Jiajun Wang , Yuan Chang , Yu Xia , Yiwei Wang , Li Liu , Yu Zhu , Le Xu , Bo Dai , Jianming Guo , Zewei Wang , Qi Bai & Weijuan Zhang
旺财体育: 1810489
Published online: 28 Aug 2020
Abstract | Full Text | References | PDF (3247 KB) | Supplemental | Permissions聽

  • 272Views
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Author鈥檚 view

The consensus Immunoscore in phase 3 clinical trials; potential impact on patient management decisions
Franck Pag猫s , Julien Taieb , Pierre Laurent-Puig & J茅r么me Galon
旺财体育: 1812221
Published online: 28 Aug 2020
Abstract | Full Text | References | PDF (590 KB) | Permissions聽

  • 296Views
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Review

Immune responses during COVID-19 infection
Cl茅a Melenotte , Aymeric Silvin , Anne-Ga毛lle Goubet , Imran Lahmar , Agathe Dubuisson , Alimuddin Zumla , Didier Raoult , Mansouria Merad , Bertrand Gachot , Cl茅mence H茅non , Eric Solary , Michaela Fontenay , Fabrice Andr茅 , Markus Maeurer , Giuseppe Ippolito , Mauro Piacentini , Fu-Sheng Wang , Florent Ginhoux , Aur茅lien Marabelle , Guido Kroemer , Lisa Derosa & Laurence Zitvogel
旺财体育: 1807836
Published online: 25 Aug 2020
Abstract | Full Text | References | PDF (6062 KB) | Permissions聽

  • 1780Views
  • 1CrossRef citations
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Brief report

brief report
Anti-tumor immunity influences cancer cell reliance upon ATG7
Michael D. Arensman , Xiaoran S. Yang , Wenyan Zhong , Stephanie Bisulco , Erik Upeslacis , Edward C. Rosfjord , Shibing Deng , Robert T. Abraham & Christina H. Eng
旺财体育: 1800162
Published online: 23 Aug 2020
Abstract | Full Text | References | PDF (5340 KB) | Supplemental | Permissions聽

  • 397Views
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Editorial

editorial
NK cells beat T cells at early breast cancer control
Aitziber Buque , Norma Bloy , Giulia Petroni , Guido Kroemer & Lorenzo Galluzzi
旺财体育: 1806010
Published online: 23 Aug 2020
Abstract | Full Text | References | PDF (558 KB) | Permissions聽

  • 394Views
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Original research

旺财体育
Adjuvant MUC vaccination with tecemotide after resection of colorectal liver metastases: a randomized, double-blind, placebo-controlled, multicenter AIO phase II trial (LICC)
Carl Christoph Schimanski , Stefan Kasper , Susanna Hegewisch-Becker , Jan Schr枚der , Friedrich Overkamp , Frank Kullmann , Wolf Otto Bechstein , Matthias V枚hringer , Robert 脰llinger , Florian Lordick , Volker Heinemann , Michael Gei脽ler , Armin Schulz-Abelius , Helga Bernhard , Michael R. Sch枚n , Richard Greil , Peter Galle , Hauke Lang , Irene Schmidtmann & Markus Moehler
旺财体育: 1806680
Published online: 23 Aug 2020
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  • 466Views
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Brief report

brief report
Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice
Lien Van Hoecke , Stephanie Riederer , Xavier Saelens , Gerd Sutter & Juan Jos茅 Rojas
旺财体育: 1802968
Published online: 20 Aug 2020
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  • 634Views
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Original research

旺财体育
Immune vulnerability of ovarian cancer stem-like cells due to low CD47 expression is protected by surrounding bulk tumor cells
Chih-Long Chang , Chao-Chih Wu , Yun-Ting Hsu & Yi-Chiung Hsu
旺财体育: 1803530
Published online: 20 Aug 2020
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  • 379Views
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Author鈥檚 Views

旺财体育
Metastasis immune-based scores predict patient survival
Bernhard Mlecnik , Gabriela Bindea , Marc Van den Eynde & J茅r么me Galon
旺财体育: 1806000
Published online: 20 Aug 2020
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  • 332Views
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Brief report

brief report
IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice
Leland G. Richardson , Linda T. Nieman , Anat O. Stemmer-Rachamimov , Xijin S. Zheng , Khalifa Stafford , Hiroaki Nagashima , Julie J. Miller , Juri Kiyokawa , David T. Ting , Hiroaki Wakimoto , Daniel P. Cahill , Bryan D. Choi & William T. Curry
旺财体育: 1806662
Published online: 20 Aug 2020
Abstract | Full Text | References | PDF (2211 KB) | Supplemental | Permissions聽

  • 705Views
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Original research

旺财体育
Potential lung attack and lethality generated by EpCAM-specific CAR-T cells in immunocompetent mouse models
Diyuan Qin , Dan Li , Benxia Zhang , Yue Chen , Xuelian Liao , Xiaoyu Li , Peter B. Alexander , Yongsheng Wang & Qi-Jing Li
旺财体育: 1806009
Published online: 15 Aug 2020
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  • 526Views
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旺财体育
Intratumoral CCR5+ neutrophils identify immunogenic subtype muscle-invasive bladder cancer with favorable prognosis and therapeutic responses
Zhuoyi Xiang , Quan Zhou , Han Zeng , Zewei Wang , Hongyu Zhang , Zhaopei Liu , Qiuren Huang , Yuan Chang , Qi Bai , Yu Xia , Yiwei Wang , Li Liu , Yu Zhu , Le Xu , Bo Dai , Jiajun Wang , Jianming Guo & Jiejie Xu
旺财体育: 1802176
Published online: 12 Aug 2020
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  • 348Views
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旺财体育
Immune surveillance activation after neoadjuvant therapy for esophageal adenocarcinoma and complete response
Andromachi Kotsafti , Melania Scarpa , Francesco Cavallin , Matteo Fassan , Roberta Salmaso , Andrea Porzionato , Luca Saadeh , Matteo Cagol , Rita Alfieri , Carlo Castoro , Massimo Rugge , Ignazio Castagliuolo & Marco Scarpa
旺财体育: 1804169
Published online: 12 Aug 2020
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  • 332Views
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Brief report

brief report
Tropomyosin autoantibodies associated with checkpoint inhibitor myositis
Pauline Zaenker , David Prentice & Melanie Ziman
旺财体育: 1804703
Published online: 12 Aug 2020
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  • 279Views
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Author鈥檚 view

Characterization of the human tumor microbiome reveals tumor-type specific intra-cellular bacteria
Ilana Livyatan , Deborah Nejman , Noam Shental & Ravid Straussman
旺财体育: 1800957
Published online: 29 Jul 2020
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  • 620Views
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Editorial

editorial
Mitochondrial control of innate immune signaling by irradiated cancer cells
Takahiro Yamazaki & Lorenzo Galluzzi
旺财体育: 1797292
Published online: 22 Jul 2020
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  • 466Views
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editorial
Lurbinectedin: an FDA-approved inducer of immunogenic cell death for the treatment of small-cell lung cancer
Oliver Kepp , Laurence Zitvogel & Guido Kroemer
旺财体育: 1795995
Published online: 21 Jul 2020
Abstract | Full Text | References | PDF (745 KB) | Permissions聽

  • 440Views
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Review

Trial Watch: experimental TLR7/TLR8 agonists for oncological indications
Giorgio Frega , Qi Wu , Julie Le Naour , Erika Vacchelli , Lorenzo Galluzzi , Guido Kroemer & Oliver Kepp
旺财体育: 1796002
Published online: 21 Jul 2020
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  • 955Views
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Brief report

brief report
Surface-exposed and soluble calreticulin: conflicting biomarkers for cancer prognosis
Oliver Kepp , Peng Liu , Liwei Zhao , Isabelle Plo & Guido Kroemer
旺财体育: 1792037
Published online: 20 Jul 2020
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  • 378Views
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Review

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors
Romain Daill猫re , Bertrand Routy , Anne-Ga毛lle Goubet , Alexandria Cogdill , Gladys Ferrere , Carolina Alves-Costa Silva , Aur茅lie Fluckiger , Pierre Ly , Yacine Haddad , Eugenie Pizzato , Cassandra Thelemaque , Marine Fidelle , Marine Mazzenga , Maria Paula Roberti , Cl茅a Melenotte , Peng Liu , Safae Terrisse , Oliver Kepp , Guido Kroemer , Laurence Zitvogel & Lisa Derosa
旺财体育: 1794423
Published online: 20 Jul 2020
Abstract | Full Text | References | PDF (1080 KB) | Permissions聽

  • 631Views
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Author鈥檚 view

The consensus Immunoscore in phase 3 clinical trial (N0147) and impact on patient management decisions
Anastasia Lanzi , F. A. Sinicrope , A. B. Benson & J茅r么me Galon
旺财体育: 1796003
Published online: 20 Jul 2020
Abstract | Full Text | References | PDF (888 KB) | Permissions聽

  • 364Views
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Original research

旺财体育
B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma
Claudia Minici , Elena Rigamonti , Marco Lanzillotta , Antonella Monno , Lucrezia Rovati , Takashi Maehara , Naoki Kaneko , Vikram Deshpande , Maria Pia Protti , Lucia De Monte , Cristina Scielzo , Stefano Crippa , Paolo Giorgio Arcidiacono , Erica Dugnani , Lorenzo Piemonti , Massimo Falconi , Shiv Pillai , Angelo A. Manfredi & Emanuel Della-Torre
旺财体育: 1794359
Published online: 16 Jul 2020
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  • 623Views
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Point-of-View

Repurposing CD8+ T cell immunity against SARS-CoV-2 for cancer immunotherapy: a positive aspect of the COVID-19 pandemic?
Shashi Gujar , Jonathan G. Pol , Youra Kim & Guido Kroemer
旺财体育: 1794424
Published online: 16 Jul 2020
Abstract | Full Text | References | PDF (1061 KB) | Permissions聽

  • 1223Views
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Original research

旺财体育
Colon-specific immune microenvironment regulates cancer progression versus rejection
Giulia Trimaglio , Anne-Fran莽oise Tilkin-Mariam茅 , Virginie Feliu , Fran莽oise Lauz茅ral-Vizcaino , Marie Tosolini , Carine Valle , Maha Ayyoub , Olivier Neyrolles , Nathalie Vergnolle , Yoann Rombouts & Christel Devaud
旺财体育: 1790125
Published online: 12 Jul 2020
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  • 380Views
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旺财体育
Specific immune landscapes and immune checkpoint expressions in histotypes and molecular subtypes of sarcoma
A. Dufresne , T. Lesluyes , C. M茅n茅trier-Caux , M. Brahmi , E. Darbo , M. Toulmonde , A. Italiano , O. Mir , A. Le Cesne , S. Le Guellec , T. Valentin , C. Chevreau , S. Bonvalot , Y.M. Robin , J-M Coindre , C. Caux , J.Y. Blay & F. Chibon
旺财体育: 1792036
Published online: 12 Jul 2020
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  • 440Views
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Author鈥檚 view

SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-伪4
Lorena Carmona-Rodr铆guez , Diego Mart铆nez-Rey , Emilia Mira & Santos Ma帽es
旺财体育: 1794163
Published online: 12 Jul 2020
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  • 263Views
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The consensus immunoscore: toward a new classification of colorectal cancer
Anastasia Lanzi , Franck Pag猫s , Christine Lagorce-Pag猫s & J茅r么me Galon
旺财体育: 1789032
Published online: 11 Jul 2020
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  • 534Views
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Original research

旺财体育
Complete and long-lasting clinical responses in immune checkpoint inhibitor-resistant, metastasized melanoma treated with adoptive T cell transfer combined with DC vaccination
Tanja L枚vgren , Maria Wolodarski , Stina Wickstr枚m , Ulrika Edb盲ck , Mette Wallin , Eva Martell , Katrin Markland , Pontus Blomberg , Maria Nystr枚m , Andreas Lundqvist , Hans Jacobsson , Gustav Ullenhag , Per Ljungman , Johan Hansson , Giuseppe Masucci , Roger Tell , Isabel Poschke , Lars Adamson , Jonas Mattsson & Rolf Kiessling
旺财体育: 1792058
Published online: 11 Jul 2020
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  • 1639Views
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Author鈥檚 view

IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection
Karsten A. Pilones , Maud Charpentier , Elena Garcia-Martinez & Sandra Demaria
旺财体育: 1790716
Published online: 09 Jul 2020
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  • 310Views
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Original research

旺财体育
Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses
Peng Liu , Liwei Zhao , Gladys Ferrere , Carolina Alves-Costa-Silva , Pierre Ly , Qi Wu , Ai-Ling Tian , Lisa Derosa , Laurence Zitvogel , Oliver Kepp & Guido Kroemer
旺财体育: 1789284
Published online: 08 Jul 2020
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  • 773Views
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Editorial

editorial
An unexpected link between immunogenic cell death and inhibition of gene transcription
Juliette Humeau , Allan Sauvat , Oliver Kepp & Guido Kroemer
旺财体育: 1792039
Published online: 08 Jul 2020
First Page Preview | Full Text | References | PDF (1626 KB) | Permissions聽

  • 215Views
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Original research

旺财体育
Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy
Anja Feldmann , Anja Hoffmann , Ralf Bergmann , Stefanie Koristka , Nicole Berndt , Claudia Arndt , Liliana Rodrigues Loureiro , Enrico Kittel-Boselli , Nicola Mitwasi , Alexandra Kegler , Chris Lamprecht , Karla Elizabeth Gonz谩lez Soto & Michael Bachmann
旺财体育: 1785608
Published online: 03 Jul 2020
Abstract | Full Text | References | PDF (10704 KB) | Supplemental | Permissions聽

  • 661Views
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旺财体育
Age-related mutational signature negatively associated with immune activity and survival outcome in triple-negative breast cancer
Hao Chen , Wei Chong , Xiaorong Yang , Yuan Zhang , Shaowei Sang , Xiangchun Li & Ming Lu
旺财体育: 1788252
Published online: 30 Jun 2020
Abstract | Full Text | References | PDF (6170 KB) | Supplemental | Permissions聽

  • 669Views
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旺财体育
Serum CCL27 predicts the response to Bacillus Calmette-Guerin immunotherapy in non-muscle-invasive bladder cancer
Wenlong Zhong , Bo Wang , Hao Yu , Jianxun Lin , Kun Xia , Weibin Hou , Meihua Yang , Junyu Chen , Meng Yang , Xiaofei Wang , Jian Huang & Tianxin Lin
旺财体育: 1776060
Published online: 27 Jun 2020
Abstract | Full Text | References | PDF (6460 KB) | Supplemental | Permissions聽

  • 327Views
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旺财体育
Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy
Ava Vila-Leahey , Alecia MacKay , Liliana Portales-Cervantes , Genevieve M. Weir , Alexandra Merkx-Jacques & Marianne M. Stanford
旺财体育: 1782574
Published online: 27 Jun 2020
Abstract | Full Text | References | PDF (4268 KB) | Supplemental | Permissions聽

  • 648Views
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旺财体育
A meta-analysis comparing responses of Asian versus non-Asian cancer patients to PD-1 and PD-L1 inhibitor-based therapy
Ling Peng , Bao-Dong Qin , Kui Xiao , Song Xu , Jin-Song Yang , Yuan-Sheng Zang , Justin Stebbing & Li-Ping Xie
旺财体育: 1781333
Published online: 26 Jun 2020
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  • 754Views
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Brief report

brief report
Tumor mutational burden is not predictive of cytotoxic chemotherapy response
Mina Nikanjam , Paul Riviere , Aaron Goodman , Donald A. Barkauskas , Garrett Frampton & Razelle Kurzrock
旺财体育: 1781997
Published online: 24 Jun 2020
Abstract | Full Text | References | PDF (669 KB) | Permissions聽

  • 501Views
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Original Research

旺财体育
Systemic inflammation is associated with circulating cell death released keratin 18 fragments in colorectal cancer
P盲ivi Sirni枚 , Juha P. V盲yrynen , Shivaprakash J. Mutt , Karl-Heinz Herzig , Jaroslaw Walkowiak , Kai Klintrup , Jyrki M盲kel盲 , Tuomo J. Karttunen , Markus J. M盲kinen & Anne Tuomisto
旺财体育: 1783046
Published online: 24 Jun 2020
Abstract | Full Text | References | PDF (1584 KB) | Supplemental | Permissions聽

  • 358Views
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Original research

旺财体育
The role of circulating monocytes and JAK inhibition in the infectious-driven inflammatory response of myelofibrosis
Martina Barone , Lucia Catani , Francesca Ricci , Marco Romano , Dorian Forte , Giuseppe Auteri , Daniela Bartoletti , Emanuela Ottaviani , Pier Luigi Tazzari , Nicola Vianelli , Michele Cavo & Francesca Palandri
旺财体育: 1782575
Published online: 23 Jun 2020
Abstract | Full Text | References | PDF (5161 KB) | Supplemental | Permissions聽

  • 680Views
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Original Research

旺财体育
Identification of tumor-infiltrating immune cells and prognostic validation of tumor-infiltrating mast cells in adrenocortical carcinoma: results from bioinformatics and real-world data
Xi Tian , Wenhao Xu , Yuchen Wang , Aihetaimujiang Anwaier , Hongkai Wang , Fangning Wan , Yu Zhu , Dalong Cao , Guohai Shi , Yiping Zhu , Yuanyuan Qu , Hailiang Zhang & Dingwei Ye
旺财体育: 1784529
Published online: 23 Jun 2020
Abstract | Full Text | References | PDF (14191 KB) | Supplemental | Permissions聽

  • 521Views
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Original research

旺财体育
A liposomal RNA vaccine inducing neoantigen-specific CD4+ T cells augments the antitumor activity of local radiotherapy in mice
Nadja Salomon , Fulvia Vascotto , Abderaouf Selmi , Mathias Vormehr , Juliane Quinkhardt , Thomas Bukur , Barbara Schr枚rs , Martin L枚ewer , Mustafa Diken , 脰zlem T眉reci , Ugur Sahin & Sebastian Kreiter
旺财体育: 1771925
Published online: 22 Jun 2020
Abstract | Full Text | References | PDF (10967 KB) | Supplemental | Permissions聽

  • 1089Views
  • 1CrossRef citations
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Original Research

旺财体育
Inflammation and lymphocyte infiltration are associated with shorter survival in patients with high-grade glioma
Eliana Marinari , Mathilde Allard , Robin Gustave , Val茅rie Widmer , G茅raldine Philippin , Doron Merkler , Petros Tsantoulis , Val茅rie Dutoit & Pierre-Yves Dietrich
旺财体育: 1779990
Published online: 21 Jun 2020
Abstract | Full Text | References | PDF (5367 KB) | Supplemental | Permissions聽

  • 525Views
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Original research

旺财体育
Impact of pseudoprogression and treatment beyond progression on outcome in patients with non-small cell lung cancer treated with immune checkpoint inhibitors
Sang Eun Won , Hyo Jung Park , Sangil Byun , Junhee Pyo , Jwa Hoon Kim , Chang-Min Choi , Jae Cheol Lee , Dae Ho Lee , Sang-We Kim , Shinkyo Yoon & Kyung Won Kim
旺财体育: 1776058
Published online: 19 Jun 2020
Abstract | Full Text | References | PDF (1882 KB) | Supplemental | Permissions聽

  • 554Views
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Review

The role of trogocytosis in immune surveillance of Hodgkin lymphoma
Qun Zeng & Herbert Schwarz
旺财体育: 1781334
Published online: 17 Jun 2020
Abstract | Full Text | References | PDF (687 KB) | Permissions聽

  • 391Views
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Original research

旺财体育
Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells
Luis Augusto Aguirre , Karla Montalb谩n-Hern谩ndez , Jos茅 Avenda帽o-Ortiz , Elvira Mar铆n , Roberto Lozano , V铆ctor Toledano , Laura S谩nchez-Maroto , Ver贸nica Terr贸n , Jaime Valent铆n , Elisa Pulido , Jos茅 Carlos Casalvilla , Carolina Rubio , Luke Diekhorst , Fernando Laso-Garc铆a , Carlos del Fresno , Ana Collazo-Lorduy , Beatriz Jim茅nez-Munarriz , Paloma G贸mez-Campelo , Emilio Llanos-Gonz谩lez , Mar铆a Fern谩ndez-Velasco , Carlos Rodr铆guez-Antol铆n , Rebeca P茅rez de Diego , Ram贸n Cantero-Cid , Enrique Hern谩dez-Jimenez , Enrique 脕lvarez , Roc铆o Rosas , Blanca dies L贸pez-Ayll贸n , Javier de Castro , Stefanie K. Wculek , Carolina Cubillos-Zapata , Inmaculada Ib谩帽ez de C谩ceres , Prudencio D铆az-Agero , Mar铆a Guti茅rrez Fern谩ndez , Mar铆a Paz de Miguel , David Sancho , Leon Schulte , Rosario Perona , Crist贸bal Belda-Iniesta , Lisardo Bosc谩 & Eduardo L贸pez-Collazo
旺财体育: 1773204
Published online: 16 Jun 2020
Abstract | Full Text | References | PDF (10640 KB) | Supplemental | Permissions聽

  • 1483Views
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旺财体育
Efficacy and safety of immune checkpoint inhibitors in patients with advanced non鈥搒mall cell lung cancer (NSCLC): a systematic literature review
Gernot Wagner , Hannah Karolina Stollenwerk , Irma Klerings , Martin Pecherstorfer , Gerald Gartlehner & Josef Singer
旺财体育: 1774314
Published online: 16 Jun 2020
Abstract | Full Text | References | PDF (3899 KB) | Supplemental | Permissions聽

  • 729Views
  • 1CrossRef citations
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旺财体育
IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils
Melanie Kienzl , Carina Hasenoehrl , Paulina Valadez-Cosmes , Kathrin Maitz , Arailym Sarsembayeva , Eva Sturm , Akos Heinemann , Julia Kargl & Rudolf Schicho
旺财体育: 1776059
Published online: 16 Jun 2020
Abstract | Full Text | References | PDF (4650 KB) | Supplemental | Permissions聽

  • 738Views
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Review

Trial watch: STING agonists in cancer therapy
Julie Le Naour , Laurence Zitvogel , Lorenzo Galluzzi , Erika Vacchelli & Guido Kroemer
旺财体育: 1777624
Published online: 16 Jun 2020
Abstract | Full Text | References | PDF (921 KB) | Permissions聽

  • 2894Views
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Tumor-derived exosomes: the next generation of promising cell-free vaccines in cancer immunotherapy
Marzieh Naseri , Mahmood Bozorgmehr , Margot Z枚ller , Ehsan Ranaei Pirmardan & Zahra Madjd
旺财体育: 1779991
Published online: 16 Jun 2020
Abstract | Full Text | References | PDF (2638 KB) | Permissions聽

  • 937Views
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Trial watch: IDO inhibitors in cancer therapy
Julie Le Naour , Lorenzo Galluzzi , Laurence Zitvogel , Guido Kroemer & Erika Vacchelli
旺财体育: 1777625
Published online: 14 Jun 2020
Abstract | Full Text | References | PDF (618 KB) | Permissions聽

  • 1224Views
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Author鈥檚 view

Turning tolerogenic into immunogenic ileal cell death through ileal microbiota: the key to unlock the mystery of colon cancer immunoscore?
Maria Paula Roberti , Marion Picard , Satoru Yonekura & Laurence Zitvogel
旺财体育: 1778834
Published online: 14 Jun 2020
Abstract | Full Text | References | PDF (697 KB) | Permissions聽

  • 412Views
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Original research

旺财体育
Adoptive cell therapy of triple negative breast cancer with redirected cytokine-induced killer cells
Roberta Sommaggio , Elisa Cappuzzello , Anna Dalla Piet脿 , Anna Tosi , Pierangela Palmerini , Debora Carpanese , Lorenzo Nicol猫 & Antonio Rosato
旺财体育: 1777046
Published online: 11 Jun 2020
Abstract | Full Text | References | PDF (5351 KB) | Permissions聽

  • 708Views
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旺财体育
Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients
Tian Zhang , Sarabjot Pabla , Felicia L. Lenzo , Jeffrey M. Conroy , Mary K. Nesline , Sean T. Glenn , Antonios Papanicolau-Sengos , Blake Burgher , Vincent Giamo , Jonathan Andreas , Yirong Wang , Wiam Bshara , Katherine G. Madden , Keisuke Shirai , Konstantin Dragnev , Laura J. Tafe , Rajan Gupta , Jason Zhu , Matthew Labriola , Shannon McCall , Daniel J. George , Pooja Ghatalia , Farshid Dayyani , Robert Edwards , Michelle S Park , Rajbir Singh , Robin Jacob , Saby George , Bo Xu , Matthew Zibelman , Razelle Kurzrock & Carl Morrison
旺财体育: 1773200
Published online: 10 Jun 2020
Abstract | Full Text | References | PDF (1855 KB) | Supplemental | Permissions聽

  • 905Views
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旺财体育
Clinical and immune responses to anti-CD3 x anti-EGFR bispecific antibody armed activated T cells (EGFR BATs) in pancreatic cancer patients
Lawrence G. Lum , Archana Thakur , Minsig Choi , Abhinav Deol , Vidya Kondadasula , Dana Schalk , Kristie Fields , Melissa Dufrense , Philip Philip , Gregory Dyson , Hussein D. Aon & Anthony F. Shields
旺财体育: 1773201
Published online: 10 Jun 2020
Abstract | Full Text | References | PDF (6261 KB) | Permissions聽

  • 650Views
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Review

Current Clinical Evidence and Potential Solutions to Increase Benefit of CAR T-Cell Therapy for Patients with Solid Tumors
Marion Alcantara , Pauline Du Rusquec & Emanuela Romano
旺财体育: 1777064
Published online: 10 Jun 2020
Abstract | Full Text | References | PDF (497 KB) | Permissions聽

  • 822Views
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Author鈥檚 view

Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms
Mrinmoy Das , Emmanuel Stephen-Victor & Jagadeesh Bayry
旺财体育: 1773193
Published online: 05 Jun 2020
Abstract | Full Text | References | PDF (600 KB) | Permissions聽

  • 305Views
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Original research

旺财体育
Modeling human pediatric and adult gliomas in immunocompetent mice through costimulatory blockade
Xiaoyan Lan , Dorota A. Kedziorek , Chengyan Chu , Anna Jablonska , Shen Li , Mihoko Kai , Yajie Liang , Miroslaw Janowski & Piotr Walczak
旺财体育: 1776577
Published online: 05 Jun 2020
Abstract | Full Text | References | PDF (4448 KB) | Supplemental | Permissions聽

  • 499Views
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Review

Standard therapies: solutions for improving therapeutic effects of immune checkpoint inhibitors on colorectal cancer
Tingting Liang , Weihua Tong , Siyang Ma & Pengyu Chang
旺财体育: 1773205
Published online: 03 Jun 2020
Abstract | Full Text | References | PDF (920 KB) | Permissions聽

  • 424Views
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Original research

旺财体育
Myeloid deletion of phosphoinositide-dependent kinase-1 enhances NK cell-mediated antitumor immunity by mediating macrophage polarization
Yuexi He , Juan Du & Zhongjun Dong
旺财体育: 1774281
Published online: 03 Jun 2020
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Review

Trial watch : the gut microbiota as a tool to boost the clinical efficacy of anticancer immunotherapy
Romain Daill猫re , Lisa Derosa , M茅lodie Bonvalet , Nicola Segata , Bertrand Routy , Manuela Gariboldi , Eva Budinsk谩 , I. Jolanda M. De Vries , Alessio Gordon Naccarati , Val茅rie Zitvogel , Carlos Caldas , Lars Engstrand , Sibylle Loilbl , Jacques Fieschi , Lucie Heinzerling , Guido Kroemer & Laurence Zitvogel
旺财体育: 1774298
Published online: 03 Jun 2020
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Original research

旺财体育
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients
Maria-Filothei Lazaridou , Evamaria Gonschorek , Chiara Massa , Michael Friedrich , Diana Handke , Anja Mueller , Simon Jasinski-Bergner , Reinhard Dummer , Peter Koelblinger & Barbara Seliger
旺财体育: 1774323
Published online: 03 Jun 2020
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  • 321Views
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旺财体育
A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy
Ana Victoria Casades煤s , Claire Deligne , B茅r茅 Kadjdiatou Diallo , Katya Sosa , Nathalie Josseaume , Circe Mesa , Kalet Le贸n , Tays Hern谩ndez & Jean-Luc Teillaud
旺财体育: 1770565
Published online: 02 Jun 2020
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Review

Trial watch: TLR3 agonists in cancer therapy
Julie Le Naour , Lorenzo Galluzzi , Laurence Zitvogel , Guido Kroemer & Erika Vacchelli
旺财体育: 1771143
Published online: 02 Jun 2020
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Original research

旺财体育
A novel gene signature to predict immune infiltration and outcome in patients with prostate cancer
Ning Shao , Hong Tang , Yuanyuan Mi , Yao Zhu , Fangning Wan & Dingwei Ye
旺财体育: 1762473
Published online: 01 Jun 2020
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  • 617Views
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旺财体育
The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines
Stine Emilie Weis-Banke , Mie Linder H眉bbe , Morten Orebo Holmstr枚m , Mia Aaboe J酶rgensen , Simone Kloch Bendtsen , Evelina Martinenaite , Marco Carretta , Inge Marie Svane , Niels 脴dum , Ayako Wakatsuki Pedersen , 脰zcan Met , Daniel Hargb酶l Madsen & Mads Hald Andersen
旺财体育: 1771142
Published online: 01 Jun 2020
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  • 507Views
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Original Research

旺财体育
Cancer immunotherapy using a polysaccharide from Codium fragile in a murine model
Hae-Bin Park , Seong-Min Lim , Juyoung Hwang , Wei Zhang , SangGuan You & Jun-O Jin
旺财体育: 1772663
Published online: 01 Jun 2020
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旺财体育
Anti-EGF antibodies as surrogate biomarkers of clinical efficacy in stage IIIB/IV non-small-cell lung cancer patients treated with an optimized CIMAvax-EGF vaccination schedule
Xitlally Popa , Beatriz Garc铆a , Karla P. Fuentes , Vivian Huerta , Karen Alvarez , Carmen E. Viada , Elia Neninger , Pedro C. Rodr铆guez , Zuyen Gonz谩lez , Amnely Gonz谩lez , Tania Crombet & Zaima Mazorra
旺财体育: 1762465
Published online: 25 May 2020
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Brief Report

brief report
Genomic and immunologic correlates of LAG-3 expression in cancer
Anshuman Panda , Jeffrey A. Rosenfeld , Eric A. Singer , Gyan Bhanot & Shridar Ganesan
旺财体育: 1756116
Published online: 22 May 2020
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  • 761Views
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Original research

旺财体育
Tumor microenvironment remodeling by an engineered oncolytic adenovirus results in improved outcome from PD-L1 inhibition
Victor Cervera-Carrascon , Dafne C.A. Quixabeira , Joao Manuel Santos , Riikka Havunen , Sadia Zafar , Otto Hemminki , Camilla Heini枚 , Eleonora Munaro , Mikko Siurala , Suvi Sorsa , Tuomas Mirtti , Petrus J盲rvinen , Markus Mildh , Harry Nisen , Antti Rannikko , Marjukka Anttila , Anna Kanerva & Akseli Hemminki
旺财体育: 1761229
Published online: 22 May 2020
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  • 895Views
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Review

Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis
Boris Shulgin , Yuri Kosinsky , Andrey Omelchenko , Lulu Chu , Ganesh Mugundu , Sergey Aksenov , Rodrigo Pimentel , Garrett DeYulia , Geoffrey Kim , Kirill Peskov & Gabriel Helmlinger
旺财体育: 1748982
Published online: 21 May 2020
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  • 753Views
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Original Research

旺财体育
Tumors escape immunosurveillance by overexpressing the proteasome activator PSME3
Mathilde Boulpicante , Romain Darrigrand , Alison Pierson , Val茅rie Salgues , Marine Rouillon , Benoit Gaudineau , Mehdi Khaled , Angela Cattaneo , Angela Bachi , Paolo Cascio & S茅bastien Apcher
旺财体育: 1761205
Published online: 21 May 2020
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  • 792Views
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旺财体育
Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide
Adam C. Mirando , Akash Patil , Christine I. Rafie , Brian J. Christmas , Niranjan B. Pandey , Vered Stearns , Elizabeth M. Jaffee , Evanthia T. Roussos Torres & Aleksander S. Popel
旺财体育: 1760685
Published online: 14 May 2020
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  • 548Views
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旺财体育
Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation
Gyu Jin Lee , Yukyung Jun , Hae Yong Yoo , Yoon Kyung Jeon , Daekee Lee , Sanghyuk Lee & Jaesang Kim
旺财体育: 1746553
Published online: 13 May 2020
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  • 432Views
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Original research

旺财体育
MMP2 as an independent prognostic stratifier in oral cavity cancers
Caroline Hoffmann , Sophie Vacher , Phil茅mon Sirven , Charlotte Lecerf , Lucile Massenet , Aur茅lie Moreira , Aurore Surun , Anne Schnitzler , Jerzy Klijanienko , Odette Mariani , Emmanuelle Jeannot , Nathalie Badois , Maria Lesnik , Olivier Choussy , Christophe Le Tourneau , Maude Guillot-Delost , Maud Kamal , Ivan Bieche & Vassili Soumelis
旺财体育: 1754094
Published online: 13 May 2020
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  • 401Views
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Original Research

旺财体育
Heat shock protein 90伪 in thymic epithelial tumors and non-thymomatous myasthenia gravis
J眉rgen Thanner , Christine Bekos , Cecilia Veraar , Stefan Janik , Maria Laggner , Panja M Boehm , Ana-Iris Schiefer , Leonhard M眉llauer , Walter Klepetko , Hendrik Jan Ankersmit & Bernhard Moser
旺财体育: 1756130
Published online: 13 May 2020
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  • 562Views
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旺财体育
Intravital imaging reveals synergistic effect of CAR T-cells and radiation therapy in a preclinical immunocompetent glioblastoma model
Surya Murty , Samuel T. Haile , Corinne Beinat , Amin Aalipour , Israt S. Alam , Tara Murty , Travis M. Shaffer , Chirag B. Patel , Edward E. Graves , Crystal L. Mackall & Sanjiv S. Gambhir
旺财体育: 1757360
Published online: 13 May 2020
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  • 1042Views
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旺财体育
Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
Mathias Vormehr , Sophie Lehar , Lena M. Kranz , Siri Tahtinen , Yoko Oei , Vincent Javinal , L茅lia Delamarre , Kerstin C. Walzer , Mustafa Diken , Sebastian Kreiter , Ira Mellman , Ugur Sahin , Jill M. Schartner & 脰zlem T眉reci
旺财体育: 1758004
Published online: 13 May 2020
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  • 529Views
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旺财体育
Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model
Xuan Ye , Janelle C. Waite , Ankur Dhanik , Namita Gupta , Maggie Zhong , Christina Adler , Evangelia Malahias , Min Ni , Yi Wei , Cagan Gurer , Wen Zhang , Lynn E. Macdonald , Andrew J. Murphy , Matthew A. Sleeman & Dimitris Skokos
旺财体育: 1758602
Published online: 13 May 2020
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  • 1109Views
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旺财体育
Transimmunization restores immune surveillance and prevents recurrence in a syngeneic mouse model of ovarian cancer
Ayesha B. Alvero , Douglas Hanlon , Mary Pitruzzello , Renata Filler , Eve Robinson , Olga Sobolev , Roslyn Tedja , Alessandra Ventura , Marcus Bosenberg , Patrick Han , Richard L. Edelson & Gil Mor
旺财体育: 1758869
Published online: 13 May 2020
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  • 437Views
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Brief Report

brief report
Endoscopical and pathological dissociation in severe colitis induced by immune-checkpoint inhibitors
Carlos Eduardo de Andrea , Jose Luis Perez-Gracia , Eduardo Castanon , Mariano Ponz-Sarvise , Jose I. Echeveste , Ignacio Melero , Miguel F. Sanmamed & Maria Esperanza Rodriguez-Ruiz
旺财体育: 1760676
Published online: 13 May 2020
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  • 421Views
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Original Research

旺财体育
Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome
Kim L. Brunekreeft , Sterre T. Paijens , Maartje C.A. Wouters , Fenne L. Komdeur , Florine A. Eggink , Joyce M. Lubbers , Hagma H. Workel , Elisabeth C. Van Der Slikke , Noor E.J. Pr枚pper , Ninke Leffers , Julien Adam , Harry Pijper , Annechien Plat , Arjan Kol , Hans W. Nijman & Marco De Bruyn
旺财体育: 1760705
Published online: 13 May 2020
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  • 539Views
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旺财体育
Blood eosinophilic relative count is prognostic for breast cancer and associated with the presence of tumor at diagnosis and at time of relapse
Concetta Elisa Onesti , Claire Josse , Delphine Boulet , J茅r么me Thiry , Barbara Beaumecker , Vincent Bours & Guy Jerusalem
旺财体育: 1761176
Published online: 13 May 2020
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  • 840Views
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旺财体育
IL-17 suppresses the therapeutic activity of cancer vaccines through the inhibition of CD8+ T-cell responses
Gilles Dadaglio , Catherine Fayolle , Marine Oberkampf , Alexandre Tang , Francesc Rudilla , Isabelle Couillin , Eirik A. Torheim , Pierre Rosenbaum & Claude Leclerc
旺财体育: 1758606
Published online: 12 May 2020
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  • 402Views
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旺财体育
ROS1-fusion protein induces PD-L1 expression via MEK-ERK activation in non-small cell lung cancer
Zheng Liu , Kejia Zhao , Shiyou Wei , Chengwu Liu , Jiankang Zhou , Qiheng Gou , Xia Wu , Zhenyu Yang , Yanbo Yang , Yong Peng , Qing Cheng & Lunxu Liu
旺财体育: 1758003
Published online: 06 May 2020
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  • 719Views
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Editorial

editorial
COVID-19: a challenge for oncology services
Bertrand Routy , Lisa Derosa , Laurence Zitvogel & Guido Kroemer
旺财体育: 1760686
Published online: 05 May 2020
First Page Preview | Full Text | References | PDF (917 KB) | Permissions聽

  • 708Views
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Correction

旺财体育
Correction
Pages: 1-2
Published online: 03 May 2020
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Original Research

旺财体育
Bendamustine with total body irradiation conditioning yields tolerant T-cells while preserving T-cell-dependent graft-versus-leukemia
Jessica Stokes , Emely A. Hoffman , Megan S. Molina , Nicole Kummet , Richard J. Simpson , Yi Zeng & Emmanuel Katsanis
旺财体育: 1758011
Published online: 30 Apr 2020
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  • 573Views
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旺财体育
Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer
Katherine R. Walter , Justin M. Balko & Christy R. Hagan
旺财体育: 1758547
Published online: 30 Apr 2020
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  • 453Views
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Editorial

editorial
The ambiguous role of FPR1 in immunity and inflammation
Erika Vacchelli, Julie Le Naour & Guido Kroemer
旺财体育: 1760061
Published online: 30 Apr 2020
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  • 473Views
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Original Research

旺财体育
Heterogeneity of immune microenvironment in ovarian cancer and its clinical significance: a retrospective study
Yue Gao, Lingxi Chen, Guangyao Cai, Xiaoming Xiong, Yuan Wu, Ding Ma, Shuai Cheng Li & Qinglei Gao
旺财体育: 1760067
Published online: 30 Apr 2020
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  • 802Views
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旺财体育
Prognostic value of CD73 expression in resected colorectal cancer liver metastasis
Nouredin Messaoudi, Isabelle Cousineau, Elizabeth Arslanian, David Henault, David Stephen, Franck Vandenbroucke-Menu, Michel Dagenais, Richard L茅tourneau, Maryl猫ne Plasse, Andr茅 Roy, R茅al Lapointe, Dirk Ysebaert, Dominique Trudel, Genevi猫ve Soucy, John Stagg & Simon Turcotte
旺财体育: 1746138
Published online: 23 Apr 2020
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  • 598Views
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旺财体育
The prognostic role of NK cells and their ligands in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis
Sangeeta K. Bisheshar, Emma J. De Ruiter, Lot A. Devriese & Stefan M. Willems
旺财体育: 1747345
Published online: 23 Apr 2020
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  • 648Views
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Original research

旺财体育
CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models
Zhuangwei Lv, Ping Zhang, Dandan Li, Mengting Qin, Longzhu Nie, Xiaoqian Wang, Li Ai, Zhaozu Feng, Woodvine Otieno Odhiambo, Yunfeng Ma & Yanhong Ji
旺财体育: 1747688
Published online: 21 Apr 2020
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  • 856Views
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Brief report

brief report
Results of the phase I open label clinical trial SAKK 06/14 assessing safety of intravesical instillation of VPM1002BC, a recombinant mycobacterium Bacillus Calmette Gu茅rin (BCG), in patients with non-muscle invasive bladder cancer and previous failure of conventional BCG therapy
Cyrill A. Rentsch, Piet Bosshard, Gr茅goire Mayor, Malte Rieken, Heike P眉schel, Gr茅gory Wirth, Richard Cathomas, Gerald P. Parzmair, Leander Grode, Bernd Eisele, Hitt Sharma, Manish Gupta, Sunil Gairola, Umesh Shaligram, Daniel Goldenberger, Fran莽ois Spertini, R茅gine Audran, Milica Enoiu, Simona Berardi, Stefanie Hayoz & Andreas Wickifor the Swiss Group for Clinical Cancer Research (SAKK)
旺财体育: 1748981
Published online: 21 Apr 2020
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  • 585Views
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Editorial

editorial
FLT3LG - a biomarker reflecting clinical responses to the immunogenic cell death inducer oxaliplatin
Jonathan G. Pol, Julie Le Naour & Guido Kroemer
旺财体育: 1755214
Published online: 21 Apr 2020
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  • 723Views
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Brief Report

brief report
Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma
Edda Bl眉mel , Shamaila Munir Ahmad , Claudia Nastasi , Andreas Willerslev-Olsen , Maria Gluud , Simon Fredholm , Tengpeng Hu , Bas G. J. Surewaard , Lise M. Lindahl , Hanne Fogh , Sergei B. Koralov , Lise Mette Rahbek Gjerdrum , Rachael A. Clark , Lars Iversen , Thorbj酶rn Krejsgaard , Charlotte Menn茅 Bonefeld , Carsten Geisler , J眉rgen C. Becker , Anders Woetmann , Mads Hald Andersen , Terkild Brink Buus & Niels 脴dum
旺财体育: 1751561
Published online: 17 Apr 2020
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  • 618Views
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Original Research

旺财体育
Efficacy of adjuvant cytokine-induced killer cell immunotherapy in patients with colorectal cancer after radical resection
Qiu-Zhong Pan, Jing-Jing Zhao, Chao-Pin Yang, Yu-Qing Zhou, Jun-Zhong Lin, Yan Tang, Jia-Mei Gu, Qi-Jing Wang, Yong-Qiang Li, Jia He, Shi-Ping Chen, Meng-Jia Song, Yue Huang, Jie-Ying Yang, De-Sheng Weng & Jian-Chuan Xia
旺财体育: 1752563
Published online: 17 Apr 2020
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  • 436Views
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旺财体育
Development of CAR-T cell therapy for B-ALL using a point-of-care approach
Luiza de Macedo Abdo, Luciana Rodrigues Carvalho Barros, Mariana Saldanha Viegas, Luisa Vieira Code莽o Marques, Priscila de Sousa Ferreira, Leonardo Chicaybam & Mart铆n Hern谩n Bonamino
旺财体育: 1752592
Published online: 17 Apr 2020
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  • 1927Views
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旺财体育
Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma
Joseph R. Podojil, Alexander P. Glaser, Dylan Baker, Elise T. Courtois, Damiano Fantini, Yanni Yu, Valerie Eaton, Santhosh Sivajothi, Mingyi Chiang, Arighno Das, Kimberly A. McLaughlin, Paul Robson, Stephen D. Miller & Joshua J. Meeks
旺财体育: 1744897
Published online: 16 Apr 2020
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  • 998Views
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旺财体育
Doxorubicin pretreatment enhances FAP伪/survivin co-targeting DNA vaccine anti-tumor activity primarily through decreasing peripheral MDSCs in the 4T1 murine breast cancer model
Fei Geng, Xin Bao, Ling Dong, Qian-Qian Guo, Jie Guo, Yu Xie, Yi Zhou, Bin Yu, Hui Wu, Jia-Xin Wu, Hai-Hong Zhang, Xiang-Hui Yu & Wei Kong
旺财体育: 1747350
Published online: 16 Apr 2020
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  • 566Views
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旺财体育
Hypoxia increases mutational load of breast cancer cells through frameshift mutations
Goutham Hassan Venkatesh, Pamela Bravo, Walid Shaaban Moustafa Elsayed, Francis Amirtharaj, Bartosz Wojtas, Raefa Abou Khouzam, Husam Hussein Nawafleh, Sandeep Mallya, Kapaettu Satyamoorthy, Philippe Dessen, Filippo Rosselli, Jerome Thiery & Salem Chouaib
旺财体育: 1750750
Published online: 16 Apr 2020
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  • 668Views
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旺财体育
Effect of excess weight and immune-related adverse events on the efficacy of cancer immunotherapy with anti-PD-1 antibodies
Jacobo Rogado, Nuria Romero-Laorden, Jos茅 Miguel Sanchez-Torres, Ana Mar铆a Ramos-Levi, Vilma Pacheco-Barcia, Ana Isabel Ballesteros, Reyes Arranz, Alicia Lorenzo, Pedro Gullon, Ana Garrido, Jos茅 Mar铆a Serra L贸pez-Matencio, Olga Donnay, Magdalena Adrados, Pablo Costas, Javier Aspa, Arantzazu Alfranca, Rebeca Mondejar & Ramon Colomer
旺财体育: 1751548
Published online: 16 Apr 2020
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  • 775Views
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旺财体育
ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance
Jacob J. Orme, Khalid A. Jazieh, Tiancheng Xie, Susan Harrington, Xin Liu, Matthew Ball, Benjamin Madden, M. Cristine Charlesworth, Tariq U. Azam, Fabrice Lucien, Bharath Wootla, Yanli Li, Jose Caetano Villasboas, Aaron S. Mansfield, Roxana S. Dronca & Haidong Dong
旺财体育: 1744980
Published online: 14 Apr 2020
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  • 1034Views
  • 1CrossRef citations
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Original research

旺财体育
Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response
Mei Song, Chao Wang, Huan Wang, Tuo Zhang, Jiuqi Li, Robert Benezra, Lotfi Chouchane, Yin-Hao Sun, Xin-Gang Cui & Xiaojing Ma
旺财体育: 1746148
Published online: 14 Apr 2020
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  • 664Views
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Original Research

旺财体育
Regulatory T cells and cytotoxic T cells close to the epithelial鈥搒tromal interface are associated with a favorable prognosis
Julian Rudolf, Maike B眉ttner-Herold, Katharina Erlenbach-W眉nsch, Rebecca Posselt, Jonas Jessberger, Marlen Haderlein, Markus Hecht, Arndt Hartmann, Rainer Fietkau & Luitpold Distel
旺财体育: 1746149
Published online: 14 Apr 2020
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  • 331Views
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Review

review
Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion
Mumtaz Y. Balkhi
旺财体育: 1747349
Published online: 14 Apr 2020
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  • 1534Views
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Original Research

旺财体育
B7-H3 inhibits the IFN-纬-dependent cytotoxicity of V纬9V未2 T cells against colon cancer cells
Huimin Lu, Tongguo Shi, Mingyuan Wang, Xiaomi Li, Yanzheng Gu, Xueguang Zhang, Guangbo Zhang & Weichang Chen
旺财体育: 1748991
Published online: 14 Apr 2020
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  • 579Views
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旺财体育
An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial
Julie Charles, Laurence Chaperot, Dalil Hannani, Juliana Bruder Costa, Isabelle Templier, Sabiha Trabelsi, Hugo Gil, Anaick Moisan, Virginie Persoons, Harald Hegelhofer, Edith Schir, Jean-Louis Quesada, Christophe Mendoza, Caroline Aspord, Olivier Manches, Pierre G. Coulie, Amir Khammari, Brigitte Dreno, Marie-Th茅r猫se Leccia & Joel Plumas
旺财体育: 1738812
Published online: 12 Apr 2020
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  • 1009Views
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旺财体育
Effectiveness and safety of nivolumab in the treatment of lung cancer patients in France: preliminary results from the real-world EVIDENS study
Fabrice Barlesi, Adrien Dixmier, Didier Debieuvre, Christophe Raspaud, Jean-Bernard Auliac, Nicolas Benoit, Pierre Bombaron, Denis Moro-Sibilot, Clarisse Audigier-Valette, Bernard Asselain, Thomas Egenod, Audrey Rabeau, J茅r么me Fayette, Myriam Locatelli Sanchez, Jean-Luc Labourey, Virginie Westeel, Pauline Lamoureux, Fran莽ois-Emery Cotte, Victoria Allan, Melinda Daumont, Juliette Dumanoir, Doroth茅e Reynaud, Christophe Yannick Calvet, Nicolas Ozan & Maurice P茅rol
旺财体育: 1744898
Published online: 12 Apr 2020
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  • 779Views
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旺财体育
Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas
Amanda R. Dancsok, Dongxia Gao, Anna F. Lee, Sonja Eriksson Steigen, Jean-Yves Blay, David M. Thomas, Robert G. Maki, Torsten O. Nielsen & Elizabeth G. Demicco
旺财体育: 1747340
Published online: 12 Apr 2020
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  • 1231Views
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旺财体育
Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal functions
Kerri Wolf-Dennen, Nancy Gordon & Eugenie S. Kleinerman
旺财体育: 1747677
Published online: 12 Apr 2020
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  • 776Views
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旺财体育
T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma
Yang Zhang, Poorva Mudgal, Liuyang Wang, Haiyang Wu, Na Huang, Peter B. Alexander, Zhixian Gao, Nan Ji & Qi-Jing Li
旺财体育: 1749476
Published online: 12 Apr 2020
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  • 565Views
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旺财体育
Tumor-infiltrating IL-17A+ cells determine favorable prognosis and adjuvant chemotherapeutic response in muscle-invasive bladder cancer
Zewei Wang, Quan Zhou, Han Zeng, Hongyu Zhang, Zhaopei Liu, Qiuren Huang, Ying Xiong, Jiajun Wang, Yuan Chang, Qi Bai, Yu Xia, Yiwei Wang, Yu Zhu, Le Xu, Bo Dai, Li Liu, Jianming Guo & Jiejie Xu
旺财体育: 1747332
Published online: 10 Apr 2020
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  • 397Views
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旺财体育
Enhanced expression of CD39 and CD73 on T cells in the regulation of anti-tumor immune responses
Ivan Shevchenko, Andreas Mathes, Christopher Groth, Svetlana Karakhanova, Verena M眉ller, Jochen Utikal, Jens Werner, Alexandr V. Bazhin & Viktor Umansky
旺财体育: 1744946
Published online: 09 Apr 2020
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  • 980Views
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旺财体育
Liver metastases and the efficacy of the PD-1 or PD-L1 inhibitors in cancer: a meta-analysis of randomized controlled trials
Shan Li, Shanquan Sun, Hui Xiang, Jing Yang, Minyong Peng & Qing Gao
旺财体育: 1746113
Published online: 09 Apr 2020
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  • 777Views
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Brief Report

brief report
Moderate-to-severe eosinophilia induced by treatment with immune checkpoint inhibitors: 37 cases from a national reference center for hypereosinophilic syndromes and the French pharmacovigilance database
Quentin Scanvion, Johana B茅n茅, Sophie Gautier, Aur茅lie Grandvuillemin, Christine Le Beller, Chouki Chenaf, Nicolas Etienne, Solenn Brousseau, Alexis B. Cortot, Laurent Mortier, Delphine Staumont-Sall茅, Franck Morschhauser, Alexandra Forestier, Matthieu Groh, David Launay, Eric Hachulla, Myriam Labalette, Jean-Emmanuel Kahn & Guillaume Lef猫vrethe French Pharmacovigilance Network, and the French reference center for hypereosinophilic syndromes (CEREO)
旺财体育: 1722022
Published online: 07 Apr 2020
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Original Research

旺财体育
Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells
SeongJun Han, Douglas C. Chung, Michael St. Paul, Zhe Qi Liu, Carlos Garcia-Batres, Alisha R. Elford, Charles W. Tran, Laurence Chapatte & Pamela S. Ohashi
旺财体育: 1737368
Published online: 07 Apr 2020
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  • 890Views
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旺财体育
Cancer immunotherapy based on blocking immune suppression mediated by an immune modulator LAIR-1
Lijun Xu, Shanlong Wang, Jufeng Li, Jie Li & Bingyu Li
旺财体育: 1740477
Published online: 07 Apr 2020
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  • 895Views
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Review

review
Identifying optimal first-line interventions for advanced non-small cell lung carcinoma according to PD-L1 expression: a systematic review and network meta-analysis
Jie Liu, Chengming Li, Samuel Seery, Jinming Yu & Xue Meng
旺财体育: 1746112
Published online: 07 Apr 2020
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  • 1732Views
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Original Research

旺财体育
CD200 and CD200R1 are differentially expressed and have differential prognostic roles in non-small cell lung cancer
Katsuhiro Yoshimura, Yuzo Suzuki, Yusuke Inoue, Kazuo Tsuchiya, Masato Karayama, Yuji Iwashita, Tomoaki Kahyo, Akikazu Kawase, Masayuki Tanahashi, Hiroshi Ogawa, Naoki Inui, Kazuhito Funai, Kazuya Shinmura, Hiroshi Niwa, Haruhiko Sugimura & Takafumi Suda
旺财体育: 1746554
Published online: 07 Apr 2020
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  • 695Views
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旺财体育
Tumor-associated tertiary lymphoid structure predicts postoperative outcomes in patients with primary gastrointestinal stromal tumors
Qiaowei Lin, Ping Tao, Jiongyuan Wang, Lijie Ma, Quan Jiang, Jinglei Li, Ge Zhang, Ju Liu, Yong Zhang, Yingyong Hou, Weiqi Lu, Ruyi Xue & Hanxing Tong
旺财体育: 1747339
Published online: 07 Apr 2020
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  • 603Views
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旺财体育
CD44v3 protein-carrying tumor-derived exosomes in HNSCC patients鈥� plasma as potential noninvasive biomarkers of disease activity
Marie-Nicole Theodoraki, Akihiro Matsumoto, Inga Beccard, Thomas K. Hoffmann & Theresa L. Whiteside
旺财体育: 1747732
Published online: 07 Apr 2020
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  • 477Views
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旺财体育
UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells
Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, Justyna Jureczek, Ralf Bergmann, Domokos M谩th茅, Nikolett Heged眉s, Nicole Berndt, Stefanie Koristka, Nicola Mitwasi, Frederick Fasslrinner, Chris Lamprecht, Alexandra Kegler, Anja Hoffmann, Tabea Bartsch, Ay艧e Sedef K枚seer, Gary Egan, Marc Schmitz, Vaclav Ho艡ej拧铆, Mechthild Krause, Anna Dubrovska & Michael Bachmann
旺财体育: 1743036
Published online: 05 Apr 2020
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  • 1281Views
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旺财体育
Heterogeneity of exhausted T cells in the tumor microenvironment is linked to patient survival following resection in hepatocellular carcinoma
Fangming Liu, Weiren Liu, David E. Sanin, Guangshuai Jia, Mengxin Tian, Han Wang, Bijun Zhu, Yan Lu, Tiankui Qiao, Xiangdong Wang, Yinghong Shi & Duojiao Wu
旺财体育: 1746573
Published online: 05 Apr 2020
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  • 887Views
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Brief Report

brief report
The immunosuppressive phenotype of tumor-infiltrating neutrophils is associated with obesity in kidney cancer patients
Camilla Margaroli, Maria A. Cardenas, Caroline S. Jansen, Adriana Moon Reyes, Fares Hosseinzadeh, Gordon Hong, Yilin Zhang, Haydn Kissick, Rabindra Tirouvanziam & Viraj A. Master
旺财体育: 1747731
Published online: 05 Apr 2020
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  • 620Views
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Point-of-View

opinion
聽RRx-001, a first-in-class small molecule inhibitor of MYC and a downregulator of CD47, is an "erythrophagoimmunotherapeutic"
Bryan Oronsky, Corey A. Carter, Scott Caroen, Curtis Scribner, Arnold Oronsky & Tony R. Reid
旺财体育: 1746172
Published online: 03 Apr 2020
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  • 411Views
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Original research

旺财体育
Identification and validation of poor prognosis immunoevasive subtype of muscle-invasive bladder cancer with tumor-infiltrating podoplanin+ cell abundance
Quan Zhou, Zewei Wang, Han Zeng, Hongyu Zhang, Zhaopei Liu, Qiuren Huang, Jiajun Wang, Yuan Chang, Qi Bai, Li Liu, Yu Zhu, Le Xu, Bo Dai, Jianming Guo, Yu Xia, Yiwei Wang & Jiejie Xu
旺财体育: 1747333
Published online: 03 Apr 2020
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  • 352Views
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Original Research

旺财体育
Identification and characterization of M6903, an antagonistic anti鈥揟IM-3 monoclonal antibody
Dong Zhang, Feng Jiang, Rinat Zaynagetdinov, Hui Huang, Vanita D. Sood, Hong Wang, Xinyan Zhao, Molly H. Jenkins, Qingyong Ji, Youbin Wang, David P. Nannemann, Djordje Musil, John Wesolowski, Andrea Paoletti, Tin Bartholomew, Melissa G. Derner, Qi An, Christel Iffland & Joern-Peter Halle
旺财体育: 1744921
Published online: 01 Apr 2020
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  • 1539Views
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旺财体育
HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer
Yingxue Ren, Yesesri Cherukuri, Daniel P. Wickland, Vivekananda Sarangi, Shulan Tian, Jodi M. Carter, Aaron S. Mansfield, Matthew S. Block, Mark E. Sherman, Keith L. Knutson, Yi Lin & Yan W. Asmann
旺财体育: 1744947
Published online: 01 Apr 2020
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  • 899Views
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旺财体育
Immune co-culture cell microarray 鈥� a feasible tool for high-throughput functional investigation of lymphocyte鈥揷ancer interactions
Erez Nissim Baruch, Rona Ortenberg, Camila Avivi, Liat Anafi, Daniela Dick-Necula, Chani Stossel, Yonatan Moshkovits, Orit Itzhaki, Michal Judith Besser, Jacob Schachter, Iris Barshack & Gal Markel
旺财体育: 1741267
Published online: 25 Mar 2020
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  • 506Views
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旺财体育
Evaluation of PD-L1 expression on circulating tumor cells (CTCs) in patients with advanced urothelial carcinoma (UC)
Sonja Bergmann , Anja Coym , Leonie Ott , Armin Soave , Michael Rink , Melanie Janning , Malgorzata Stoupiec , Cornelia Coith , Sven Peine , Gunhild von Amsberg , Klaus Pantel & Sabine Riethdorf
旺财体育: 1738798
Published online: 23 Mar 2020
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  • 918Views
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旺财体育
Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination
Wouter W. van Willigen, Martine Bloemendal, Marye J. Boers-Sonderen, Jan Willem B. de Groot, Rutger H.T. Koornstra, Astrid A.M. van der Veldt, John B. A. G. Haanen, Steve Boudewijns, Gerty Schreibelt, Winald R. Gerritsen, I. Jolanda M. de Vries & Kalijn F. Bol
旺财体育: 1738814
Published online: 22 Mar 2020
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  • 473Views
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旺财体育
Osteosarcoma and soft-tissue sarcomas with an immune infiltrate express PD-L1: relation to clinical outcome and Th1 pathway activation
Jay S. Wunder, Minji J. Lee, Junghyun Nam, Beatrice Y. Lau, Brendan C. Dickson, Dushanthi Pinnaduwage, Shelley B. Bull, Peter C. Ferguson, Andrew Seto, Nalan Gokgoz & Irene L. Andrulis
旺财体育: 1737385
Published online: 18 Mar 2020
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  • 593Views
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旺财体育
Blockade of programmed cell death protein 1 (PD-1) in S茅zary syndrome reduces Th2 phenotype of non-tumoral T lymphocytes but may enhance tumor proliferation
Ieva Saulite, Desislava Ignatova, Yun-Tsan Chang, Christina Fassnacht, Florentia Dimitriou, Eleni Varypataki, Florian Anzengruber, Mirjam N盲geli, Antonio Cozzio, Reinhard Dummer, Julia Scarisbrick, Steve Pascolo, Wolfram Hoetzenecker, Malgorzata Bobrowicz & Emmanuella Guenova
旺财体育: 1738797
Published online: 18 Mar 2020
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  • 545Views
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旺财体育
Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses
Yusuf D枚len, Michael Valente, Oya Tagit, Eliezer J盲ger, Eric A. W. Van Dinther, N. Koen van Riessen, Martin Hruby, Uzi Gileadi, Vincenzo Cerundolo & Carl G. Figdor
旺财体育: 1738813
Published online: 17 Mar 2020
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  • 720Views
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旺财体育
LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures
Nicolas Gestermann, Damien Saugy, Christophe Martignier, Laure Till茅, Silvia A. Fuertes Marraco, Markus Zettl, I帽igo Tirapu, Daniel E. Speiser & Gr茅gory Verdeil
旺财体育: 1736792
Published online: 12 Mar 2020
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  • 935Views
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旺财体育
Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq
Santiago J. Carmona, Imran Siddiqui, Mariia Bilous, Werner Held & David Gfeller
旺财体育: 1737369
Published online: 12 Mar 2020
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  • 2973Views
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Original research

旺财体育
Integration of intratumoral RASSF10 expression and tumor-associated macrophages into the established clinical indicators better predicts the prognosis of clear cell renal cell carcinoma patients
Chao Wang, Tianyu Hong, Yuning Wang, Sishun Gan, Qifeng Wang, Jian Li, Li Zuo & Xingang Cui
旺财体育: 1736793
Published online: 11 Mar 2020
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  • 407Views
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Original Research

旺财体育
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
Maria Georganaki, Mohanraj Ramachandran, Sander Tuit, Nicol谩s Gonzalo N煤帽ez, Alexandros Karampatzakis, Grammatiki Fotaki, Luuk van Hooren, Hua Huang, Roberta Lugano, Thomas Ulas, Aura Kaunisto, Eric C Holland, Peter Ellmark, Sara M Mangsbo, Joachim Schultze, Magnus Essand, Sonia Tugues & Anna Dimberg
旺财体育: 1730538
Published online: 09 Mar 2020
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  • 1029Views
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旺财体育
Complement inhibitor factor H expressed by breast cancer cells differentiates CD14+ human monocytes into immunosuppressive macrophages
Karolina I. Smolag, Christine M. Mueni, Karin Leandersson, Karin Jirstr枚m, Catharina Hagerling, Matthias M枚rgelin, Paul N. Barlow, Myriam Martin & Anna M. Blom
旺财体育: 1731135
Published online: 06 Mar 2020
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  • 615Views
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旺财体育
PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis
Fatmah A. Mansour, Amer Al-Mazrou, Falah Al-Mohanna, Monther Al-Alwan & Hazem Ghebeh
旺财体育: 1729299
Published online: 03 Mar 2020
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  • 1144Views
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Brief Report

brief report
Prophylactic and therapeutic antileukemic effects induced by the AAC-11-derived Peptide RT53
Justine Habault, Anna Kaci, Ewa Pasquereau-Kotula, Claire Fraser, Christine Chomienne, Herv茅 Dombret, Thorsten Braun, Marika Pla & Jean-Luc Poyet
旺财体育: 1728871
Published online: 02 Mar 2020
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  • 482Views
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Original Research

旺财体育
A TP53-associated gene signature for prediction of prognosis and therapeutic responses in lung squamous cell carcinoma
Feng Xu, Haoyu Lin, Pei He, Lulu He, Jiexin Chen, Ling Lin & Yongsong Chen
旺财体育: 1731943
Published online: 02 Mar 2020
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  • 1507Views
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旺财体育
Deep neural network classification based on somatic mutations potentially predicts clinical benefit of immune checkpoint blockade in lung adenocarcinoma
Jie Peng, Dan Zou, Wuxing Gong, Shuai Kang & Lijie Han
旺财体育: 1734156
Published online: 29 Feb 2020
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  • 962Views
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旺财体育
Valproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression
Zhiqi Xie, Tamami Ikegami, Yukio Ago, Naoki Okada & Masashi Tachibana
旺财体育: 1734268
Published online: 29 Feb 2020
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  • 764Views
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Review

review
Lactate dehydrogenase: a marker of diminished antitumor immunity
Sandra Van Wilpe, Rutger Koornstra, Martijn Den Brok, Jan Willem De Groot, Christian Blank, Jolanda De Vries, Winald Gerritsen & Niven Mehra
旺财体育: 1731942
Published online: 26 Feb 2020
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  • 1702Views
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Original Research

旺财体育
Oncolytic poxvirus CF33-hNIS-螖F14.5 favorably modulates tumor immune microenvironment and works synergistically with anti-PD-L1 antibody in a triple-negative breast cancer model
Shyambabu Chaurasiya, Annie Yang, Seonah Kang, Jianming Lu, Sang-In Kim, Anthony K. Park, Venkatesh Sivanandam, Zhifang Zhang, Yanghee Woo, Susanne G. Warner & Yuman Fong
旺财体育: 1729300
Published online: 24 Feb 2020
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  • 1350Views
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旺财体育
A non-linear association between blood tumor mutation burden and prognosis in NSCLC patients receiving atezolizumab
Wei Nie, Jie Qian, Mi-Die Xu, Kai Gu, Fang-Fei Qian, Min-Juan Hu, Jun Lu, Lu Gan, Xue-Yan Zhang, Shu-Hui Cao, Jing-Wen Li, Yue Wang, Bo Zhang, Shu-Yuan Wang, Fang Hu, Chang-Hui Li, Hua Zhong & Bao-Hui Han
旺财体育: 1731072
Published online: 20 Feb 2020
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  • 750Views
  • 2CrossRef citations
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旺财体育
Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity
Shumei Kato, Ryosuke Okamura, Yuichi Kumaki, Sadakatsu Ikeda, Mina Nikanjam, Ramez Eskander, Aaron Goodman, Suzanna Lee, Sean T. Glenn, Devin Dressman, Antonios Papanicolau-Sengos, Felicia L. Lenzo, Carl Morrison & Razelle Kurzrock
旺财体育: 1708065
Published online: 17 Feb 2020
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  • 1655Views
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旺财体育
Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer
Kyoko Yamaguchi, Mamoru Ito, Hirofumi Ohmura, Fumiyasu Hanamura, Michitaka Nakano, Kenji Tsuchihashi, Shuntaro Nagai, Hiroshi Ariyama, Hitoshi Kusaba, Hidetaka Yamamoto, Yoshinao Oda, Masafumi Nakamura, Koichi Akashi & Eishi Baba
旺财体育: 1724763
Published online: 17 Feb 2020
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  • 1051Views
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旺财体育
T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources
Sarah Bonte, Stijn De Munter, Glenn Goetgeluk, Joline Ingels, Melissa Pille, Lore Billiet, Tom Taghon, Georges Leclercq, Bart Vandekerckhove & Tessa Kerre
旺财体育: 1727078
Published online: 17 Feb 2020
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  • 1008Views
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旺财体育
Eosinophil accumulation predicts response to melanoma treatment with immune checkpoint inhibitors
Sonja C. S. Simon, Xiaoying Hu, Jasper Panten, Mareike Grees, Simon Renders, Daniel Thomas, Rebekka Weber, Torsten J. Schulze, Jochen Utikal & Viktor Umansky
旺财体育: 1727116
Published online: 15 Feb 2020
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  • 1195Views
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Editorial

editorial
A novel platinum-based chemotherapeutic inducing immunogenic cell death
Oliver Kepp & Guido Kroemer
旺财体育: 1729022
Published online: 15 Feb 2020
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  • 496Views
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Original Research

旺财体育
Potent immunomodulatory effects of an anti-CEA-IL-2 immunocytokine on tumor therapy and effects of stereotactic radiation
Maciej Kujawski, Mark Sherman, Susanta Hui, Darren Zuro, Wen-Hui Lee, Paul Yazaki, Anakim Sherman, Barbara Szpikowska, Junie Chea, Desiree Lasiewski, Kofi Poku, Harry Li, David Colcher, Jeffrey Wong & John E. Shively
旺财体育: 1724052
Published online: 14 Feb 2020
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  • 859Views
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旺财体育
S100A4 promotes hepatocellular carcinogenesis by intensifying fibrosis-associated cancer cell stemness
Yanan Li, Jun Wang, Kun Song, Shuangqing Liu, Huilei Zhang, Fei Wang, Chen Ni, Wenlong Zhai, Jialu Liang, Zhihai Qin & Jinhua Zhang
旺财体育: 1725355
Published online: 14 Feb 2020
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  • 776Views
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旺财体育
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system
Sjoerd Klarenbeek, Chris W. Doornebal, Sjors M. Kas, Nicola Bonzanni, Jinhyuk Bhin, Tanya M. Braumuller, Ingrid van der Heijden, Mark Opdam, Philip C. Schouten, Kelly Kersten, Roebi de Bruijn, Daniel Zingg, Julia Yemelyanenko, Lodewyk F.A. Wessels, Karin E. de Visser & Jos Jonkers
旺财体育: 1724049
Published online: 12 Feb 2020
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  • 767Views
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旺财体育
Tumor-targeting oncolytic virus elicits potent immunotherapeutic vaccine responses to tumor antigens
Yong Luo, Chaolong Lin, Yidi Zou, Fei Ju, Wenfeng Ren, Yanhua Lin, Yale Wang, Xiaoxuan Huang, Huiling Liu, Zeng Yu, Pingguo Liu, Guowei Tan, Quan Yuan, Jun Zhang, Chenghao Huang & Ningshao Xia
旺财体育: 1726168
Published online: 12 Feb 2020
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  • 1094Views
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Brief Report

brief report
PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models
Takahiro Yamazaki, Aitziber Buqu茅, Tyler D. Ames & Lorenzo Galluzzi
旺财体育: 1721810
Published online: 11 Feb 2020
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Original Research

旺财体育
Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer
Johnie Hodge, Fang Wang, Junfeng Wang, Qing Liu, Fatma Saaoud, Yuzhen Wang, Udai P. Singh, Hexin Chen, Ming Luo, Walden Ai & Daping Fan
旺财体育: 1724761
Published online: 09 Feb 2020
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Commentary

article commentary
Metabolism in the tumor microenvironment: insights from single-cell analysis
Zhengtao Xiao, Jason W. Locasale & Ziwei Dai
旺财体育: 1726556
Published online: 09 Feb 2020
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Original Research

旺财体育
Immune-related adverse events are clustered into distinct subtypes by T-cell profiling before and early after anti-PD-1 treatment
Kyung Hwan Kim, Joon Young Hur, Jinhyun Cho, Bo Mi Ku, Jiae Koh, June Young Koh, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Keunchil Park, Myung-Ju Ahn & Eui-Cheol Shin
旺财体育: 1722023
Published online: 02 Feb 2020
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旺财体育
Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment
Min Yang, Wenwen Du, Lixian Yi, Shaoxian Wu, Chunyan He, Wensi Zhai, Cuihua Yue, Runzi Sun, Ashley V. Menk, Greg M. Delgoffe, Jingting Jiang & Binfeng Lu
旺财体育: 1708064
Published online: 30 Jan 2020
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旺财体育
Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy
Mara De Martino, Mercedes Tkach, Sof铆a Bruni, Dar铆o Rocha, Mar铆a F. Mercogliano, Mauro E. Cenciarini, Mar铆a F. Chervo, Cecilia J. Proietti, Florent Dingli, Damarys Loew, Elmer A. Fern谩ndez, Patricia V. Elizalde, Eliane Piaggio & Roxana Schillaci
旺财体育: 1715767
Published online: 29 Jan 2020
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  • 999Views
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旺财体育
PD-1 blockade in neoadjuvant setting of DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer
Ding-Xin Liu, Dan-Dan Li, Wan He, Chuan-Feng Ke, Wu Jiang, Jing-Hua Tang, Ling-Heng Kong, Yuan Li, Qiao-Qi Sui, Bin-Yi Xiao, Wei-Rong Li, Zhi-Gang Hong, Rui-Hua Xu, Zhi-Zhong Pan, Xiao-Shi Zhang & Pei-Rong Ding
旺财体育: 1711650
Published online: 22 Jan 2020
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旺财体育
Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds
Denis L. Jardim, D茅bora De Melo Gagliato, Mina Nikanjam, Donald A. Barkauskas & Razelle Kurzrock
旺财体育: 1710052
Published online: 13 Jan 2020
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Brief Report

brief report
Durable tumor regression in highly refractory metastatic KIT/PDGFRA聽wild-type GIST following treatment with nivolumab
Brett A. Schroeder, Karan Kohli, Ryan B. O鈥橫alley, Theresa S. Kim, Robin L. Jones, Robert H. Pierce & Seth M. Pollack
旺财体育: 1710064
Published online: 13 Jan 2020
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Original Research

旺财体育
Therapeutic melanoma vaccine with cancer stem cell phenotype represses exhaustion and maintains antigen-specific T cell stemness by up-regulating BCL6
Patrycja Czerwinska, Marcin Rucinski, Nikola Wlodarczyk, Anna Jaworska, Iga Grzadzielewska, Katarzyna Gryska, Lukasz Galus, Jacek Mackiewicz & Andrzej Mackiewicz
旺财体育: 1710063
Published online: 11 Jan 2020
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Review

review
Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology
Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi & Abhishek D. Garg
旺财体育: 1703449
Published online: 09 Jan 2020
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Original Research

旺财体育
ASTX660, an antagonist of cIAP1/2 and XIAP, increases antigen processing machinery and can enhance radiation-induced immunogenic cell death in preclinical models of head and neck cancer
Wenda Ye, Sreenivasulu Gunti, Clint T. Allen, Youji Hong, Paul E. Clavijo, Carter Van Waes & Nicole C. Schmitt
旺财体育: 1710398
Published online: 09 Jan 2020
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旺财体育
Evaluating the role of FAMIly history of cancer and diagnosis of multiple neoplasms in cancer patients receiving PD-1/PD-L1 checkpoint inhibitors: the multicenter FAMI-L1 study
Alessio Cortellini, Sebastiano Buti, Melissa Bersanelli, Raffaele Giusti, Fabiana Perrone, Pietro Di Marino, Nicola Tinari, Michele De Tursi, Antonino Grassadonia, Katia Cannita, Alessandra Tessitore, Federica Zoratto, Enzo Veltri, Francesco Malorgio, Marco Russano, Cecilia Anesi, Tea Zeppola, Marco Filetti, Paolo Marchetti, Andrea Botticelli, Gian Carlo Antonini Cappellini, Federica De Galitiis, Maria Giuseppa Vitale, Francesca Rastelli, Federica Pergolesi, Rossana Berardi, Silvia Rinaldi, Marianna Tudini, Rosa Rita Silva, Annagrazia Pireddu, Francesco Atzori, Daniela Iacono, Maria Rita Migliorino, Alain Gelibter, Mario Alberto Occhipinti, Francesco Martella, Alessandro Inno, Stefania Gori, Sergio Bracarda, Cristina Zannori, Claudia Mosillo, Alessandro Parisi, Giampiero Porzio, Domenico Mallardo, Maria Concetta Fargnoli, Marcello Tiseo, Daniele Santini, Paolo A Ascierto & Corrado Ficorella
旺财体育: 1710389
Published online: 07 Jan 2020
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Editorial

editorial
Secreted calreticulin mutants subvert anticancer immunosurveillance
Peng Liu, Liwei Zhao, Guido Kroemer & Oliver Kepp
旺财体育: 1708126
Published online: 28 Dec 2019
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Point-of-View

opinion
In the mix: the potential benefits of adding GM-CSF to CpG-B in the local treatment of patients with early-stage melanoma
Bas D. Koster, Tamarah D. de Jong, Mari F. C. M. van den Hout, Berbel J. R. Sluijter, Ronald J. C. L. M. Vuylsteke, Barbara G. Molenkamp, Saskia Vosslamber, M. Petrousjka van den Tol, Alfons J. M. van den Eertwegh & Tanja D. de Gruijl
旺财体育: 1708066
Published online: 26 Dec 2019
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Correction

correction
Correction
Pages: 1-2
Published online: 14 Dec 2019
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Original Research

旺财体育
A pipeline for identification and validation of tumor-specific antigens in a mouse model of metastatic breast cancer
Christa I. DeVette, Harika Gundlapalli, Shu-Chin Alicia Lai, Curtis P. McMurtrey, Ashley R. Hoover, Hem R. Gurung, Wei R. Chen, Alana L. Welm & William H. Hildebrand
旺财体育: 1685300
Published online: 29 Nov 2019
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旺财体育
Preclinical evaluation of an affinity-enhanced MAGE-A4-specific T-cell receptor for adoptive T-cell therapy
Joseph P Sanderson, Darragh J Crowley, Guy E Wiedermann, Laura L Quinn, Katherine L Crossland, Helen M Tunbridge, Terri V Cornforth, Christopher S Barnes, Tina Ahmed, Karen Howe, Manoj Saini, Rachel J Abbott, Victoria E Anderson, Barbara Tavano, Miguel Maroto & Andrew B Gerry
旺财体育: 1682381
Published online: 24 Nov 2019
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旺财体育
Comedications influence immune infiltration and pathological response to neoadjuvant chemotherapy in breast cancer
Anne-Sophie Hamy, Lisa Derosa, Constance Valdeli猫vre, Satoru Yonekura, Paule Opolon, Ma毛l Priour, Julien Guerin, Jean-Yves Pierga, Bernard Asselain, Diane De Croze, Alice Pinheiro, Marick Lae, Laure-Sophie Talagrand, Enora Laas, Lauren Darrigues, Beatriz Grandal, Elisabetta Marangoni, Elodie Montaudon, Guido Kroemer, Laurence Zitvogel & Fabien Reyal
旺财体育: 1677427
Published online: 14 Nov 2019
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旺财体育
A classification based on tumor budding and immune score for patients with hepatocellular carcinoma
Li Wei, Zhang Delin, Yuan Kefei, Wu Hong, Huang Jiwei & Zhang Yange
旺财体育: 1672495
Published online: 07 Nov 2019
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  • 1348Views
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旺财体育
GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells
Christian M. Seitz, Sarah Schroeder, Philipp Knopf, Ann-Christin Krahl, Jana Hau, Sabine Schleicher, Manuela Martella, Leticia Quintanilla-Martinez, Manfred Kneilling, Bernd Pichler, Peter Lang, Daniel Atar, Karin Schilbach, Rupert Handgretinger & Patrick Schlegel
旺财体育: 1683345
Published online: 07 Nov 2019
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  • 2373Views
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旺财体育
Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome
Shaokang Ma, Jonathan Chee, Vanessa S. Fear, Catherine A. Forbes, Louis Boon, Ian M. Dick, Bruce W. S. Robinson & Jenette Creaney
旺财体育: 1684714
Published online: 07 Nov 2019
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  • 827Views
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Original research

旺财体育
The prognostic impact of immune-related adverse events during anti-PD1 treatment in melanoma and non鈥搒mall-cell lung cancer: a real-life retrospective study
R. Dupont, E. B茅rard, F. Puisset, T. Comont, J.-P. Delord, R. Guimbaud, N. Meyer, J. Mazieres & L. Alric
旺财体育: 1682383
Published online: 05 Nov 2019
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  • 1578Views
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Original Research

旺财体育
TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity
Jun-Young Lee, Eunjin Lee, Sung-Wook Hong, Daeun Kim, O. Eunju, Jonathan Sprent, Sin-Hyeog Im, You Jeong Lee & Charles D. Surh
旺财体育: 1681869
Published online: 04 Nov 2019
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  • 2060Views
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旺财体育
B7-H3 specific T cells with chimeric antigen receptor and decoy PD-1 receptors eradicate established solid human tumors in mouse models
Baozhu Huang, Liqun Luo, Jun Wang, Bailin He, Rui Feng, Na Xian, Qiong Zhang, Lieping Chen & Gangxiong Huang
旺财体育: 1684127
Published online: 04 Nov 2019
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旺财体育
Epstein鈥揃arr virus-positive diffuse large B-cell lymphoma features disrupted antigen capture/presentation and hijacked T-cell suppression
Xiang-Nan Jiang, Bao-Hua Yu, Wan-Hui Yan, Jimmy Lee, Xiao-Yan Zhou & Xiao-Qiu Li
旺财体育: 1683346
Published online: 03 Nov 2019
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旺财体育
The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia
Zi-Jun Xu, Yu Gu, Cui-Zhu Wang, Ye Jin, Xiang-Mei Wen, Ji-Chun Ma, Li-Juan Tang, Zhen-Wei Mao, Jun Qian & Jiang Lin
旺财体育: 1683347
Published online: 03 Nov 2019
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旺财体育
Isolated limb perfusion with melphalan activates interferon-stimulated genes to induce tumor regression in patients with melanoma in-transit metastasis
Junko Johansson, Roberta Kiffin, Ebru Aydin, Malin S. Nilsson, Kristoffer Hellstrand, Per Lindn茅r, Peter Naredi, Roger Olofsson Bagge & Anna Martner
旺财体育: 1684126
Published online: 03 Nov 2019
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  • 866Views
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Original research

旺财体育
Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma
Sophie Sneddon, Craig M. Rive, Shaokang Ma, Ian M. Dick, Richard J. N. Allcock, Scott D. Brown, Robert A. Holt, Mark Watson, Shay Leary, Y. C. Gary Lee, Bruce W. S. Robinson & Jenette Creaney
旺财体育: 1684713
Published online: 03 Nov 2019
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  • 1427Views
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Point-of-View

opinion
Destroy, what destroys you
Khang Luu, Emily Nickles & Herbert Schwarz
旺财体育: 1685301
Published online: 03 Nov 2019
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  • 706Views
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Original research

旺财体育
Targeting ST2 expressing activated regulatory T cells in Kras-mutant lung cancer
Byung-Seok Kim, Jelita Clinton, Qing Wang & Seon Hee Chang
旺财体育: 1682380
Published online: 02 Nov 2019
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  • 1041Views
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Original Research

旺财体育
Establishment and validation of an immunodiagnostic model for prediction of breast cancer
Cuipeng Qiu, Peng Wang, Bofei Wang, Jianxiang Shi, Xiao Wang, Tiandong Li, Jiejie Qin, Liping Dai, Hua Ye & Jianying Zhang
旺财体育: 1682382
Published online: 28 Oct 2019
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  • 805Views
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旺财体育
Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma
M. Kazim Panjwani, Matthew J. Atherton, Martha A. MaloneyHuss, Kumudhini P. Haran, Ailian Xiong, Minnal Gupta, Irina Kulikovsaya, Simon F. Lacey & Nicola J. Mason
旺财体育: 1676615
Published online: 23 Oct 2019
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  • 2312Views
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旺财体育
Close proximity of immune and tumor cells underlies response to anti-PD-1 based therapies in metastatic melanoma patients
Tuba N. Gide, Ines P. Silva, Camelia Quek, Tasnia Ahmed, Alexander M. Menzies, Matteo S. Carlino, Robyn P.M. Saw, John F. Thompson, Marcel Batten, Georgina V. Long, Richard A. Scolyer & James S. Wilmott
旺财体育: 1659093
Published online: 16 Oct 2019
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  • 1260Views
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Brief Report

brief report
Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer
Brett J. Hos , Marcel G.M. Camps , Jitske van den Bulk , Elena Tondini , Thomas C. van den Ende , Dina Ruano , Kees Franken , George M.C. Janssen , Arnoud Ru , Dmitri V. Filippov , Ramon Arens , Peter A. van Veelen , Noel Miranda & Ferry Ossendorp
旺财体育: 1673125
Published online: 13 Oct 2019
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  • 3538Views
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Review

review
The promise of adoptive cellular immunotherapies in hepatocellular carcinoma
Peter G. Hendrickson, Michael Olson, Tim Luetkens, Siani Weston, Tiffany Han, Djordje Atanackovic & Gabriel C. Fine
旺财体育: 1673129
Published online: 13 Oct 2019
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Author鈥檚 view

opinion
Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies
Yuting Ma, Heng Yang & Guido Kroemer
旺财体育: 1673635
Published online: 11 Oct 2019
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  • 1195Views
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Commentary

article commentary
Calreticulin arms NK cells against leukemia
Jitka Fucikova, Justin P. Kline, Lorenzo Galluzzi & Radek Spisek
旺财体育: 1671763
Published online: 09 Oct 2019
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  • 747Views
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